Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 227092..227237 Replicon chromosome
Accession NZ_CP093856
Organism Klebsiella pneumoniae strain Bio30

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 227128..227230 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 227092..227237 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOQ79_RS01060 222222..224282 + 2061 WP_004151449.1 oligopeptidase B -
MOQ79_RS01065 224286..224945 - 660 WP_002911407.1 exodeoxyribonuclease X -
MOQ79_RS01070 225024..225254 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MOQ79_RS01075 225367..225741 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MOQ79_RS01080 225745..226614 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
MOQ79_RS01085 226631..226969 + 339 WP_002911404.1 YebY family protein -
- 227092..227237 - 146 - - Antitoxin
- 227128..227230 + 103 - - Toxin
MOQ79_RS01090 227605..227748 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MOQ79_RS01095 227853..228821 - 969 WP_162822694.1 VirK/YbjX family protein -
MOQ79_RS01100 228978..229631 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
MOQ79_RS01105 229628..229819 - 192 WP_002911395.1 YebW family protein -
MOQ79_RS01110 229917..230156 - 240 WP_002911393.1 YebV family protein -
MOQ79_RS01115 230272..231705 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238948 NZ_CP093856:227128-227230 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238948 NZ_CP093856:c227237-227092 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References