Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5418795..5418940 Replicon chromosome
Accession NZ_CP093854
Organism Klebsiella pneumoniae strain Bio45

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5418831..5418933 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5418795..5418940 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOQ73_RS26165 5413925..5415985 + 2061 WP_004151449.1 oligopeptidase B -
MOQ73_RS26170 5415989..5416648 - 660 WP_043906809.1 exodeoxyribonuclease X -
MOQ73_RS26175 5416727..5416957 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MOQ73_RS26180 5417070..5417444 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MOQ73_RS26185 5417448..5418317 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
MOQ73_RS26190 5418334..5418672 + 339 WP_002911404.1 YebY family protein -
- 5418795..5418940 - 146 - - Antitoxin
- 5418831..5418933 + 103 - - Toxin
MOQ73_RS26195 5419309..5419452 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MOQ73_RS26200 5419557..5420525 - 969 WP_004151446.1 VirK/YbjX family protein -
MOQ73_RS26205 5420682..5421335 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
MOQ73_RS26210 5421332..5421523 - 192 WP_002911395.1 YebW family protein -
MOQ73_RS26215 5421621..5421860 - 240 WP_002911393.1 YebV family protein -
MOQ73_RS26220 5421976..5423409 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - rfaE 5360671..5607358 246687


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238933 NZ_CP093854:5418831-5418933 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238933 NZ_CP093854:c5418940-5418795 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References