Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5361248..5361393 Replicon chromosome
Accession NZ_CP093852
Organism Klebsiella pneumoniae strain Bio73

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5361255..5361357 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5361248..5361393 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOQ71_RS25890 5356779..5358212 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
MOQ71_RS25895 5358328..5358567 + 240 WP_002911393.1 YebV family protein -
MOQ71_RS25900 5358665..5358856 + 192 WP_002911395.1 YebW family protein -
MOQ71_RS25905 5358853..5359506 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
MOQ71_RS25910 5359663..5360631 + 969 WP_004151446.1 VirK/YbjX family protein -
MOQ71_RS25915 5360736..5360879 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 5361248..5361393 + 146 - - Antitoxin
- 5361255..5361357 - 103 - - Toxin
MOQ71_RS25920 5361516..5361854 - 339 WP_002911404.1 YebY family protein -
MOQ71_RS25925 5361871..5362740 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
MOQ71_RS25930 5362744..5363118 - 375 WP_004151448.1 CopC domain-containing protein YobA -
MOQ71_RS25935 5363231..5363461 + 231 WP_002911406.1 DNA polymerase III subunit theta -
MOQ71_RS25940 5363540..5364199 + 660 WP_043906809.1 exodeoxyribonuclease X -
MOQ71_RS25945 5364203..5366263 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element blaSHV-28 kdsA / iroE 5161741..5405379 243638


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238908 NZ_CP093852:c5361357-5361255 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238908 NZ_CP093852:5361248-5361393 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References