Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
Location | 1981..2540 | Replicon | plasmid unnamed1 |
Accession | NZ_CP093549 | ||
Organism | Escherichia coli strain YL03 |
Toxin (Protein)
Gene name | relE | Uniprot ID | U9YB49 |
Locus tag | MPJ80_RS24530 | Protein ID | WP_000421259.1 |
Coordinates | 2265..2540 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | U9Y625 |
Locus tag | MPJ80_RS24525 | Protein ID | WP_001178087.1 |
Coordinates | 1981..2265 (+) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MPJ80_RS24520 (46) | 46..1077 | + | 1032 | WP_000907852.1 | plasmid replication initiator RepA | - |
MPJ80_RS24525 (1981) | 1981..2265 | + | 285 | WP_001178087.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
MPJ80_RS24530 (2265) | 2265..2540 | + | 276 | WP_000421259.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
MPJ80_RS24535 (2646) | 2646..2849 | + | 204 | Protein_3 | hypothetical protein | - |
MPJ80_RS24540 (3119) | 3119..3385 | - | 267 | WP_000627832.1 | hypothetical protein | - |
MPJ80_RS24545 (3385) | 3385..3879 | - | 495 | WP_015058884.1 | hypothetical protein | - |
MPJ80_RS24550 (3935) | 3935..4537 | - | 603 | WP_000521606.1 | ProQ/FINO family protein | - |
MPJ80_RS24555 (4713) | 4713..5765 | - | 1053 | WP_000655519.1 | hypothetical protein | - |
MPJ80_RS24560 (5978) | 5978..6568 | - | 591 | WP_001401589.1 | hypothetical protein | - |
MPJ80_RS24565 (6568) | 6568..6822 | - | 255 | WP_000343106.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Conjugative plasmid | - | - | 1..89988 | 89988 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10736.45 Da Isoelectric Point: 9.9324
>T238887 WP_000421259.1 NZ_CP093549:2265-2540 [Escherichia coli]
MELKWTSKALSDLARLYDFLVLASKPAAARTVQSLTQAPVILLTHPRMGEQLFQFEPREVRRIFAGEYEIRYELTGQTIY
VLRLWHTRENR
MELKWTSKALSDLARLYDFLVLASKPAAARTVQSLTQAPVILLTHPRMGEQLFQFEPREVRRIFAGEYEIRYELTGQTIY
VLRLWHTRENR
Download Length: 276 bp
>T238887 NZ_LR890524:1714565-1714864 [Burkholderia cepacia]
ATGGACAAGATCAAGACGCGGCCGTGGGATTCGGCCGAACACCTGAAAACCGAAGACGACATGGCCGACTACTTCGACGC
ATGCCTGCAGGAGGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGCGCACGCGGCATGTCGC
AGGTCGCGCGCCATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAAGTCATCAAGGCGCTTGGCCTGCAATTGCACGGCGCCAAGGCTGCCGCGTGA
ATGGACAAGATCAAGACGCGGCCGTGGGATTCGGCCGAACACCTGAAAACCGAAGACGACATGGCCGACTACTTCGACGC
ATGCCTGCAGGAGGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCCCGCGCACGCGGCATGTCGC
AGGTCGCGCGCCATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACG
ATCCTGAAAGTCATCAAGGCGCTTGGCCTGCAATTGCACGGCGCCAAGGCTGCCGCGTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10488.92 Da Isoelectric Point: 5.6558
>AT238887 WP_001178087.1 NZ_CP093549:1981-2265 [Escherichia coli]
MQMKNNTAQATKVITAHVPLPMADKVDQMAARLERSRGWIIKQALSAWLAQEEERNRLTLEALDDVTSGQVIDHQAVQAW
ADSLSTDNPLPVPR
MQMKNNTAQATKVITAHVPLPMADKVDQMAARLERSRGWIIKQALSAWLAQEEERNRLTLEALDDVTSGQVIDHQAVQAW
ADSLSTDNPLPVPR
Download Length: 285 bp
>AT238887 NZ_LR890524:1714244-1714561 [Burkholderia cepacia]
ATGCCCTACAGTCCTCCTGCATTCAGCATCCGGACCACCGACGTCTTCGACGCCTGGTTTGCCGGCCTGCCCGATCGCCT
CGCCAAACGCCGCATTCAGGCGCGCATCGACCGCCTGTCGATGGGCAATCCGGGCGACTGGAAATCCGCCGGCTCCCCCG
TCGTCGAAATGCGTATCGACCACGGCCCCGGCTATCGCGTCTATGACGTGAGGCGCGGAACGATATGGGTCATCCTGCTG
TGCGGCGGCGATCAATCGACGCAACAGGCCGACATCCGCGCCGCGCACGCAATGCTCGCGCACCTCGACATGGAGTGA
ATGCCCTACAGTCCTCCTGCATTCAGCATCCGGACCACCGACGTCTTCGACGCCTGGTTTGCCGGCCTGCCCGATCGCCT
CGCCAAACGCCGCATTCAGGCGCGCATCGACCGCCTGTCGATGGGCAATCCGGGCGACTGGAAATCCGCCGGCTCCCCCG
TCGTCGAAATGCGTATCGACCACGGCCCCGGCTATCGCGTCTATGACGTGAGGCGCGGAACGATATGGGTCATCCTGCTG
TGCGGCGGCGATCAATCGACGCAACAGGCCGACATCCGCGCCGCGCACGCAATGCTCGCGCACCTCGACATGGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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