Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3636581..3637383 Replicon chromosome
Accession NZ_CP093528
Organism Shinella zoogloeoides strain XJ20

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag MOE34_RS18100 Protein ID WP_242218926.1
Coordinates 3636856..3637383 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag MOE34_RS18095 Protein ID WP_242218922.1
Coordinates 3636581..3636859 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOE34_RS18080 3632580..3633665 + 1086 WP_242218916.1 EpsG family protein -
MOE34_RS18085 3633699..3634820 + 1122 WP_242218918.1 glycosyltransferase family 4 protein -
MOE34_RS18090 3634851..3636170 + 1320 WP_242218920.1 sugar transferase -
MOE34_RS18095 3636581..3636859 + 279 WP_242218922.1 DUF1778 domain-containing protein Antitoxin
MOE34_RS18100 3636856..3637383 + 528 WP_242218926.1 GNAT family N-acetyltransferase Toxin
MOE34_RS18105 3637847..3638386 + 540 Protein_3572 transposase -
MOE34_RS18110 3638402..3638698 - 297 WP_242223907.1 hypothetical protein -
MOE34_RS18115 3638698..3640323 - 1626 WP_242217625.1 IS66 family transposase -
MOE34_RS18120 3640387..3640680 - 294 WP_242217624.1 IS66 family insertion sequence element accessory protein TnpB -
MOE34_RS18125 3640731..3641111 - 381 WP_242217622.1 transposase -
MOE34_RS18130 3641210..3641875 + 666 Protein_3577 IS256 family transposase -
MOE34_RS18135 3641957..3642364 + 408 WP_242218929.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(11-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18649.54 Da        Isoelectric Point: 8.1409

>T238835 WP_242218926.1 NZ_CP093528:3636856-3637383 [Shinella zoogloeoides]
MTLPAWREEAIAKSHDRQSFDCGDPAMNDFLRRYARQSHEQNASKTFCAIDVATPNRVLGFYTVAPSAIAHEVVPASMTK
GLAQHEVCGFKLARIATDVTVAGQGLGGQLLAAVALRCLRIAAEAGGVLLIIDAKGARAAQWYAGYGAEPLENRPLTLVM
PLATFAADLKAKGLL

Download         Length: 528 bp

>T238835 NZ_LR890500:4348175-4348708 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGATTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10095.66 Da        Isoelectric Point: 10.1757

>AT238835 WP_242218922.1 NZ_CP093528:3636581-3636859 [Shinella zoogloeoides]
MPQAAVDDNKRMNLRVSPETKAKLVRAAALRNTDLTNFVTQTVLREAEAVIEAAEVVRLSSRDHARVLELLENPPKPNAK
LRAAIAALPDTL

Download         Length: 279 bp

>AT238835 NZ_LR890500:4347898-4348164 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References