Detailed information of TA system TA238831

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 1119247..1119878
• Replicon: chromosome
• Accession: NZ_CP093528
• Organism: Shinella zoogloeoides strain XJ20

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: MOE34_RS05770
• Protein ID: WP_242221802.1
• Coordinates: 1119480..1119878 (+)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: MOE34_RS05765
• Protein ID: WP_242221801.1
• Coordinates: 1119247..1119480 (+)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MOE34_RS05750	1114687..1117530	+	2844	WP_242221798.1	DUF2339 domain-containing protein	-
MOE34_RS05755	1117589..1118242	+	654	WP_242221799.1	HD domain-containing protein	-
MOE34_RS05760	1118321..1119166	+	846	WP_242221800.1	MOSC domain-containing protein	-
MOE34_RS05765	1119247..1119480	+	234	WP_242221801.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
MOE34_RS05770	1119480..1119878	+	399	WP_242221802.1	tRNA(fMet)-specific endonuclease VapC	Toxin
MOE34_RS05775	1119910..1120902	-	993	WP_242221803.1	magnesium transporter CorA family protein	-
MOE34_RS05780	1121203..1122438	+	1236	WP_242221804.1	MFS transporter	-
MOE34_RS05785	1122606..1123685	+	1080	WP_242221807.1	quinolinate synthase NadA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-124)

Antitoxin

• SpoVT-AbrB domain (7-56)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 14666.95 Da
• Isoelectric Point: 7.3515

>T238831 WP_242221802.1 NZ_CP093528:1119480-1119878 [Shinella zoogloeoides]
MLAYMLDTNICIYVMKTYPPAVREKFNALAEQLCISSITLAELHYGAEKSARRAENLVAVEHFVARLEVLPFAARAAAHY
GQVRAELERAGTPCGPHDMQIGGHARSEGLIVVTNNLREFARMPGLRAENWV

Nucleotide

• Length: 399 bp

>T238831 NZ_LR890500:c2800422-2800012 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATAGCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8732.77 Da
• Isoelectric Point: 5.0493

>AT238831 WP_242221801.1 NZ_CP093528:1119247-1119480 [Shinella zoogloeoides]
MANSTVFTSNRSQAVRLPKAVAFPEDVHTVDVLKIGRSRVIVPQGQRWDDLFLNGPRVSDDFMSEREQPAAEERESF

Nucleotide

• Length: 234 bp

>AT238831 NZ_LR890500:c2800669-2800403 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA