Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 763853..764318 Replicon chromosome
Accession NZ_CP093528
Organism Shinella zoogloeoides strain XJ20

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag MOE34_RS03760 Protein ID WP_242221144.1
Coordinates 763853..764116 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag MOE34_RS03765 Protein ID WP_242221146.1
Coordinates 764103..764318 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOE34_RS03750 759246..760112 + 867 WP_242221140.1 DsbA family protein -
MOE34_RS03755 760347..763811 + 3465 WP_242221143.1 chromosome segregation protein SMC -
MOE34_RS03760 763853..764116 + 264 WP_242221144.1 BrnT family toxin Toxin
MOE34_RS03765 764103..764318 + 216 WP_242221146.1 CopG family antitoxin Antitoxin
MOE34_RS03770 764397..764543 + 147 WP_242221148.1 hypothetical protein -
MOE34_RS03775 764727..767396 + 2670 WP_242221150.1 pyruvate, phosphate dikinase -
MOE34_RS03780 767400..767645 - 246 WP_242223738.1 hypothetical protein -
MOE34_RS03785 767716..768087 - 372 WP_242221153.1 hypothetical protein -
MOE34_RS03790 768284..768763 - 480 WP_242221155.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin

CopG antitoxin

(2-69)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10230.33 Da        Isoelectric Point: 4.7453

>T238829 WP_242221144.1 NZ_CP093528:763853-764116 [Shinella zoogloeoides]
MSFEYDPEKSRSNKAKHGIDFDEVQALWQDERLIEAPARTDDEPRYLAVGMIDGRHWAAVCVRRGDSVRIISVRRAREQE
IEYYESD

Download         Length: 264 bp

>T238829 NZ_LR890500:810355-811677 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCGCCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCACCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8067.21 Da        Isoelectric Point: 6.3058

>AT238829 WP_242221146.1 NZ_CP093528:764103-764318 [Shinella zoogloeoides]
MKATEFEAKFDAGDDVAADVDWSKARRANLEMRRVNVDFPAWVVEGLDRQASRLGVTRQSLIKMWIAEKLG

Download         Length: 216 bp

>AT238829 NZ_LR890500:810089-810355 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCACTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References