Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1775066..1775211 Replicon chromosome
Accession NZ_CP093489
Organism Klebsiella pneumoniae strain VA126

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1775102..1775204 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1775066..1775211 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MO410_RS08575 1770196..1772256 + 2061 WP_004151449.1 oligopeptidase B -
MO410_RS08580 1772260..1772919 - 660 WP_080893182.1 exodeoxyribonuclease X -
MO410_RS08585 1772998..1773228 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MO410_RS08590 1773341..1773715 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MO410_RS08595 1773719..1774588 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
MO410_RS08600 1774605..1774943 + 339 WP_016529031.1 YebY family protein -
- 1775066..1775211 - 146 - - Antitoxin
- 1775102..1775204 + 103 - - Toxin
MO410_RS08605 1775580..1775723 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MO410_RS08610 1775828..1776796 - 969 WP_014907334.1 VirK/YbjX family protein -
MO410_RS08615 1776953..1777606 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
MO410_RS08620 1777603..1777794 - 192 WP_002911395.1 YebW family protein -
MO410_RS08625 1777892..1778131 - 240 WP_002911393.1 YebV family protein -
MO410_RS08630 1778247..1779680 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238758 NZ_CP093489:1775102-1775204 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238758 NZ_CP093489:c1775211-1775066 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References