Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1926081..1926226 Replicon chromosome
Accession NZ_CP093486
Organism Klebsiella pneumoniae strain VA172

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1926117..1926219 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1926081..1926226 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MO413_RS09425 1921211..1923271 + 2061 WP_004151449.1 oligopeptidase B -
MO413_RS09430 1923275..1923934 - 660 WP_080893182.1 exodeoxyribonuclease X -
MO413_RS09435 1924013..1924243 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MO413_RS09440 1924356..1924730 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MO413_RS09445 1924734..1925603 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
MO413_RS09450 1925620..1925958 + 339 WP_016529031.1 YebY family protein -
- 1926081..1926226 - 146 - - Antitoxin
- 1926117..1926219 + 103 - - Toxin
MO413_RS09455 1926595..1926738 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MO413_RS09460 1926843..1927811 - 969 WP_014907334.1 VirK/YbjX family protein -
MO413_RS09465 1927968..1928621 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
MO413_RS09470 1928618..1928809 - 192 WP_002911395.1 YebW family protein -
MO413_RS09475 1928907..1929146 - 240 WP_002911393.1 YebV family protein -
MO413_RS09480 1929262..1930695 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238739 NZ_CP093486:1926117-1926219 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238739 NZ_CP093486:c1926226-1926081 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References