Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2061664..2061809 Replicon chromosome
Accession NZ_CP093481
Organism Klebsiella pneumoniae strain VA564

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2061700..2061802 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2061664..2061809 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MO411_RS10100 2056794..2058854 + 2061 WP_004151449.1 oligopeptidase B -
MO411_RS10105 2058858..2059517 - 660 WP_080893182.1 exodeoxyribonuclease X -
MO411_RS10110 2059596..2059826 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MO411_RS10115 2059939..2060313 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MO411_RS10120 2060317..2061186 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
MO411_RS10125 2061203..2061541 + 339 WP_016529031.1 YebY family protein -
- 2061664..2061809 - 146 - - Antitoxin
- 2061700..2061802 + 103 - - Toxin
MO411_RS10130 2062178..2062321 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MO411_RS10135 2062426..2063394 - 969 WP_014907334.1 VirK/YbjX family protein -
MO411_RS10140 2063551..2064204 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
MO411_RS10145 2064201..2064392 - 192 WP_002911395.1 YebW family protein -
MO411_RS10150 2064490..2064729 - 240 WP_002911393.1 YebV family protein -
MO411_RS10155 2064845..2066278 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238719 NZ_CP093481:2061700-2061802 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238719 NZ_CP093481:c2061809-2061664 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References