Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2051187..2051331 | Replicon | chromosome |
| Accession | NZ_CP093476 | ||
| Organism | Klebsiella pneumoniae strain VA569 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2051223..2051325 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2051187..2051331 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MO417_RS10045 (MO417_10040) | 2046317..2048377 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| MO417_RS10050 (MO417_10045) | 2048381..2049040 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| MO417_RS10055 (MO417_10050) | 2049119..2049349 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| MO417_RS10060 (MO417_10055) | 2049462..2049836 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| MO417_RS10065 (MO417_10060) | 2049840..2050709 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| MO417_RS10070 (MO417_10065) | 2050726..2051064 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2051187..2051331 | - | 145 | - | - | Antitoxin |
| - | 2051223..2051325 | + | 103 | - | - | Toxin |
| MO417_RS10075 (MO417_10070) | 2051458..2051739 | - | 282 | Protein_1970 | tyrosine-type recombinase/integrase | - |
| MO417_RS10080 (MO417_10075) | 2051816..2052295 | + | 480 | WP_032419797.1 | lysis protein | - |
| MO417_RS10085 (MO417_10080) | 2052750..2052945 | + | 196 | Protein_1972 | DNA polymerase V | - |
| MO417_RS10090 (MO417_10085) | 2053084..2054589 | + | 1506 | WP_020956680.1 | hypothetical protein | - |
| MO417_RS10095 (MO417_10090) | 2054839..2055267 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| MO417_RS10100 (MO417_10095) | 2055277..2055558 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T238694 NZ_CP093476:2051223-2051325 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT238694 NZ_CP093476:c2051331-2051187 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
