Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1995968..1996113 Replicon chromosome
Accession NZ_CP093471
Organism Klebsiella pneumoniae strain VA591

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1996004..1996106 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1995968..1996113 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MO415_RS09640 1991098..1993158 + 2061 WP_032419805.1 oligopeptidase B -
MO415_RS09645 1993162..1993821 - 660 WP_002911407.1 exodeoxyribonuclease X -
MO415_RS09650 1993900..1994130 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MO415_RS09655 1994243..1994617 + 375 WP_020316569.1 CopC domain-containing protein YobA -
MO415_RS09660 1994621..1995490 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
MO415_RS09665 1995507..1995845 + 339 WP_002911404.1 YebY family protein -
- 1995968..1996113 - 146 - - Antitoxin
- 1996004..1996106 + 103 - - Toxin
MO415_RS09670 1996481..1996624 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MO415_RS09675 1996729..1997697 - 969 WP_014907334.1 VirK/YbjX family protein -
MO415_RS09680 1997854..1998507 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
MO415_RS09685 1998504..1998695 - 192 WP_002911395.1 YebW family protein -
MO415_RS09690 1998793..1999032 - 240 WP_002911393.1 YebV family protein -
MO415_RS09695 1999148..2000581 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238674 NZ_CP093471:1996004-1996106 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238674 NZ_CP093471:c1996113-1995968 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References