Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3207280..3207425 Replicon chromosome
Accession NZ_CP093465
Organism Klebsiella pneumoniae strain VA681

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3207287..3207389 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3207280..3207425 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MO412_RS15850 (MO412_15840) 3202812..3204245 + 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
MO412_RS15855 (MO412_15845) 3204361..3204600 + 240 WP_002911393.1 YebV family protein -
MO412_RS15860 (MO412_15850) 3204698..3204889 + 192 WP_002911395.1 YebW family protein -
MO412_RS15865 (MO412_15855) 3204886..3205539 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
MO412_RS15870 (MO412_15860) 3205696..3206664 + 969 WP_004151446.1 VirK/YbjX family protein -
MO412_RS15875 (MO412_15865) 3206769..3206912 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3207280..3207425 + 146 - - Antitoxin
- 3207287..3207389 - 103 - - Toxin
MO412_RS15880 (MO412_15870) 3207548..3207886 - 339 WP_016529031.1 YebY family protein -
MO412_RS15885 (MO412_15875) 3207903..3208772 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
MO412_RS15890 (MO412_15880) 3208776..3209150 - 375 WP_004151448.1 CopC domain-containing protein YobA -
MO412_RS15895 (MO412_15885) 3209263..3209493 + 231 WP_002911406.1 DNA polymerase III subunit theta -
MO412_RS15900 (MO412_15890) 3209572..3210231 + 660 WP_032425085.1 exodeoxyribonuclease X -
MO412_RS15905 (MO412_15895) 3210235..3212295 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238659 NZ_CP093465:c3207389-3207287 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238659 NZ_CP093465:3207280-3207425 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References