Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1893734..1893879 Replicon chromosome
Accession NZ_CP093458
Organism Klebsiella pneumoniae strain VA684

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1893770..1893872 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1893734..1893879 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MO416_RS09175 (MO416_09170) 1888864..1890924 + 2061 WP_004151449.1 oligopeptidase B -
MO416_RS09180 (MO416_09175) 1890928..1891587 - 660 WP_002911407.1 exodeoxyribonuclease X -
MO416_RS09185 (MO416_09180) 1891666..1891896 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MO416_RS09190 (MO416_09185) 1892009..1892383 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MO416_RS09195 (MO416_09190) 1892387..1893256 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
MO416_RS09200 (MO416_09195) 1893273..1893611 + 339 WP_002911404.1 YebY family protein -
- 1893734..1893879 - 146 - - Antitoxin
- 1893770..1893872 + 103 - - Toxin
MO416_RS09205 (MO416_09200) 1894248..1894391 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
MO416_RS09210 (MO416_09205) 1894496..1895464 - 969 WP_004151446.1 VirK/YbjX family protein -
MO416_RS09215 (MO416_09210) 1895621..1896274 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
MO416_RS09220 (MO416_09215) 1896271..1896462 - 192 WP_002911395.1 YebW family protein -
MO416_RS09225 (MO416_09220) 1896560..1896799 - 240 WP_002911393.1 YebV family protein -
MO416_RS09230 (MO416_09225) 1896915..1898348 - 1434 WP_064156927.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238636 NZ_CP093458:1893770-1893872 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238636 NZ_CP093458:c1893879-1893734 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References