Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2114347..2114492 Replicon chromosome
Accession NZ_CP093451
Organism Klebsiella pneumoniae strain VA833

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2114383..2114485 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2114347..2114492 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MO408_RS10515 2109478..2111538 + 2061 Protein_2058 oligopeptidase B -
MO408_RS10520 2111542..2112201 - 660 WP_080893182.1 exodeoxyribonuclease X -
MO408_RS10525 2112280..2112510 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MO408_RS10530 2112623..2112997 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MO408_RS10535 2113001..2113869 + 869 Protein_2062 copper homeostasis membrane protein CopD -
MO408_RS10540 2113886..2114224 + 339 WP_016529031.1 YebY family protein -
- 2114347..2114492 - 146 - - Antitoxin
- 2114383..2114485 + 103 - - Toxin
MO408_RS10545 2114861..2115004 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MO408_RS10550 2115109..2116077 - 969 WP_014907334.1 VirK/YbjX family protein -
MO408_RS10555 2116234..2116887 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
MO408_RS10560 2116884..2117075 - 192 WP_002911395.1 YebW family protein -
MO408_RS10565 2117172..2117411 - 240 WP_002911393.1 YebV family protein -
MO408_RS10570 2117526..2118958 - 1433 Protein_2069 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238615 NZ_CP093451:2114383-2114485 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238615 NZ_CP093451:c2114492-2114347 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References