Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 861952..862612 Replicon chromosome
Accession NZ_CP093445
Organism Salmonella enterica subsp. enterica serovar Abeokuta strain OG19FER4

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag MOV10_RS04145 Protein ID WP_000244756.1
Coordinates 862199..862612 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag MOV10_RS04140 Protein ID WP_000351186.1
Coordinates 861952..862218 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOV10_RS04120 (857881) 857881..859314 - 1434 WP_224939453.1 6-phospho-beta-glucosidase BglA -
MOV10_RS04125 (859472) 859472..859783 + 312 WP_242105716.1 N(4)-acetylcytidine aminohydrolase -
MOV10_RS04130 (859947) 859947..860606 + 660 WP_000250289.1 hemolysin III family protein -
MOV10_RS04135 (860722) 860722..861702 - 981 WP_000874176.1 tRNA-modifying protein YgfZ -
MOV10_RS04140 (861952) 861952..862218 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
MOV10_RS04145 (862199) 862199..862612 + 414 WP_000244756.1 protein YgfX Toxin
MOV10_RS04150 (862665) 862665..863186 - 522 WP_001055885.1 flavodoxin FldB -
MOV10_RS04155 (863299) 863299..864195 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
MOV10_RS04160 (864219) 864219..864932 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
MOV10_RS04165 (864938) 864938..866671 + 1734 WP_000813392.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T238591 WP_000244756.1 NZ_CP093445:862199-862612 [Salmonella enterica subsp. enterica serovar Abeokuta]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

>T238591 NZ_LR890406:c38203-37817 [Escherichia coli]
ATGAAATTCGTTAGTTCACAGGAAGTGATTGAGTTTCATGACCGCTTGATTTCGCGTGATGGTGGCGTGGCGGGTATGCC
AGAACCCGGTCGCGCTGACGCGATCATTCATCGTGTTTTGAACATGTATCATTATGAAGGTGTGACAGATATTATGGATC
TGGCTGCCGTGTATTTAGTTGCTATTGCTCGTGGTCACATTTTCAACGATGCAAATAAGCGAACAGCCTTGTTTGTTGCA
CAGGTTTTTTTAAAACGGAATGGTGTACATATTATTAGTTCACGTATTTCGTTTGATGAAATGCAAATTATCGCTTTGAA
TGCTGCAACAGGAGAATATAACTGGAAGATGGTTTCTGACCATCTTAAAGCCATTATTCTAAATTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT238591 WP_000351186.1 NZ_CP093445:861952-862218 [Salmonella enterica subsp. enterica serovar Abeokuta]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT238591 NZ_LR890406:c38424-38200 [Escherichia coli]
ATGTTTACATGTAACTATAGCCATGCTCGCGATAACCTGGCCTCGTTGCTCGAGCTGGCGGTTGATGAAAATCAGCCTGT
TGAGATTCAGCGCCGTAAAGGTGGCGCGGCTGTACTAGTTGATAAAGACGCTTTTGAACGATACCGTAAAGCGGCTCTTG
ATGCTGAGTTTGCTGAGATCATGCAAAGTCATGGGACGGCCTATACGGAGCTTTCTAAGCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References