Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 1092025..1092530 Replicon chromosome
Accession NZ_CP093428
Organism Pseudomonas migulae strain 8R6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MOQ58_RS04840 Protein ID WP_150631935.1
Coordinates 1092025..1092279 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MOQ58_RS04845 Protein ID WP_280163000.1
Coordinates 1092276..1092530 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOQ58_RS04820 (MOQ58_04820) 1088030..1088737 + 708 WP_008025433.1 peptide-methionine (S)-S-oxide reductase MsrA -
MOQ58_RS04825 (MOQ58_04825) 1088754..1089767 - 1014 WP_280162998.1 diguanylate cyclase -
MOQ58_RS04830 (MOQ58_04830) 1089833..1090738 - 906 WP_223450830.1 LysR family transcriptional regulator -
MOQ58_RS04835 (MOQ58_04835) 1090841..1092016 + 1176 WP_280162999.1 aspartate aminotransferase family protein -
MOQ58_RS04840 (MOQ58_04840) 1092025..1092279 - 255 WP_150631935.1 Txe/YoeB family addiction module toxin Toxin
MOQ58_RS04845 (MOQ58_04845) 1092276..1092530 - 255 WP_280163000.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
MOQ58_RS04850 (MOQ58_04850) 1092684..1093199 - 516 WP_280163001.1 adenylate kinase -
MOQ58_RS04855 (MOQ58_04855) 1093245..1095167 - 1923 WP_280163002.1 alkaline phosphatase D family protein -
MOQ58_RS04860 (MOQ58_04860) 1095251..1095634 - 384 WP_226298649.1 hypothetical protein -
MOQ58_RS04865 (MOQ58_04865) 1095712..1096254 - 543 WP_280163003.1 NAD(P)H-dependent oxidoreductase -
MOQ58_RS04870 (MOQ58_04870) 1096347..1097246 + 900 WP_223481419.1 LysR family transcriptional regulator -
MOQ58_RS04875 (MOQ58_04875) 1097227..1097472 - 246 Protein_954 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10095.51 Da        Isoelectric Point: 6.7174

>T238583 WP_150631935.1 NZ_CP093428:c1092279-1092025 [Pseudomonas migulae]
MNIEFTPEGWEDYLWFQQNDKAGLKRINLLIKSIQREPFDGLGKPEPLKHNLSGFWSRRITGEHRLVYAVEDDEIRVVMC
RYHY

Download         Length: 255 bp

>T238583 NZ_LR890405:3766872-3767090 [Escherichia coli]
ATGTCCGAAAAACCTTTAACAAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9514.96 Da        Isoelectric Point: 8.5163

>AT238583 WP_280163000.1 NZ_CP093428:c1092530-1092276 [Pseudomonas migulae]
MQTINYTTARAHLAETMDRVNEDRAPLLVTRQKGEPVVMMSLAEYNALEETAYLLRSPANAERLIKSIGNLRAGKIKTRQ
LIEE

Download         Length: 255 bp

>AT238583 NZ_LR890405:3766472-3766846 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGCAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References