Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1813149..1813420 Replicon chromosome
Accession NC_012759
Organism Escherichia coli BW2952

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1813187..1813290 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1813149..1813420 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWG_RS09075 (BWG_1649) 1810306..1811745 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BWG_RS09080 (BWG_1650) 1811863..1812099 + 237 WP_001295499.1 DUF1480 family protein -
BWG_RS09085 (BWG_1651) 1812204..1812395 + 192 WP_000457842.1 YebW family protein -
BWG_RS09090 (BWG_1652) 1812396..1813052 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1813149..1813420 + 272 - - Antitoxin
- 1813187..1813290 - 104 - - Toxin
BWG_RS09100 (BWG_1653) 1813448..1813789 - 342 WP_000976476.1 YebY family protein -
BWG_RS09105 (BWG_1654) 1813802..1814674 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
BWG_RS09110 (BWG_1655) 1814678..1815052 - 375 WP_000168747.1 CopC domain-containing protein YobA -
BWG_RS09115 (BWG_1656) 1815191..1815421 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BWG_RS09120 (BWG_1657) 1815523..1816179 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
BWG_RS09125 (BWG_1658) 1816203..1816865 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T23855 NC_012759:c1813290-1813187 [Escherichia coli BW2952]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT23855 NC_012759:1813149-1813420 [Escherichia coli BW2952]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References