Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 212881..213400 Replicon chromosome
Accession NZ_CP093376
Organism Cronobacter sakazakii strain 70402496

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MOQ97_RS01545 Protein ID WP_004385271.1
Coordinates 213113..213400 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MOQ97_RS01540 Protein ID WP_004385270.1
Coordinates 212881..213123 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOQ97_RS01525 (MOQ97_01525) 208924..210042 + 1119 WP_004385267.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
MOQ97_RS01530 (MOQ97_01530) 210039..210779 + 741 WP_004385268.1 KDGP aldolase family protein -
MOQ97_RS01535 (MOQ97_01535) 210893..212803 + 1911 WP_004385269.1 PRD domain-containing protein -
MOQ97_RS01540 (MOQ97_01540) 212881..213123 + 243 WP_004385270.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MOQ97_RS01545 (MOQ97_01545) 213113..213400 + 288 WP_004385271.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MOQ97_RS01550 (MOQ97_01550) 213408..213872 - 465 WP_004385272.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
MOQ97_RS01555 (MOQ97_01555) 214257..216392 - 2136 WP_015386331.1 anaerobic ribonucleoside-triphosphate reductase -
MOQ97_RS01560 (MOQ97_01560) 216689..217570 - 882 WP_007852197.1 LysR family transcriptional regulator -
MOQ97_RS01565 (MOQ97_01565) 217673..218203 + 531 WP_004386036.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10811.80 Da        Isoelectric Point: 10.5836

>T238331 WP_004385271.1 NZ_CP093376:213113-213400 [Cronobacter sakazakii]
MSYKLVFDPRALKEWHKLGETVKAQFKKKLAHVLAAPRVKSARLSGLPDCYKIKLRTSGYRLVYQVRDDAVCVLVIAIGK
RENLTVYQGAGHRLE

Download         Length: 288 bp

>T238331 NZ_LR890312:865434-865844 [Klebsiella oxytoca]
GTGGTCCTGTGGCAATCTGATTTACGCATCTCGTGGCGAGCGCAATGGTTCTCACTGTTGATGCACGGCGTGGTGGCGGC
GCTGGTGCTGGTGTTGCCCTGGCCGCTGAGCTATACCCCGCTGTGGCTGATACTGCTGTCGCTGGTGGTGTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGACAGGGGGAAATAAAGCTGCTGATTGACTCTCGCCTGCGCTGGCAAAAAGCG
GAGTGGGATATCGTCGGCACCCCGTGGGTAATCAATAGCGGAATGCTGCTGCGTCTGCGAAATACGGAAAACCAACGCAC
TCAGCATCTATGGGTGGCGGCGGATAGCATGGACGCGGGCGAGTGGCGCGATCTGCGTCGGCTGGTGTTACAGAAACCGA
CGCAAGATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9037.45 Da        Isoelectric Point: 5.1088

>AT238331 WP_004385270.1 NZ_CP093376:212881-213123 [Cronobacter sakazakii]
MATINVRLDDKLKNEAYAVLEKLGITPTEAVRLLFQYVAQNGRMPVKTLTVSDSEEALLRTVRERLADPRPGIRVDLDEL

Download         Length: 243 bp

>AT238331 NZ_LR890312:865187-865453 [Klebsiella oxytoca]
ATGGATATTAACAATAAAGCTCGCATCCACTGGGCATGCCGCCGGGGAATGCGTGAACTCGATATCTCCATCATGCCGTT
TTTTGAGCATGAGTACGATACGCTCAGTGATGACGATAAGCGGTTGTTCATCCGCCTGCTGGAAAATGACGATCCGGACC
TGTTCAACTGGTTGATGAACCATGGCGAACCGGCTGATGCAGAACTGCAGCGGATGGTAAAATTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References