Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2745336..2745607 Replicon chromosome
Accession NZ_CP093369
Organism Escherichia coli strain EV36 mutant 5a

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2745374..2745477 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2745336..2745607 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Q35_RS13325 2742493..2743932 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
L0Q35_RS13330 2744050..2744286 + 237 WP_001295499.1 YebV family protein -
L0Q35_RS13335 2744391..2744582 + 192 WP_000457842.1 YebW family protein -
L0Q35_RS13340 2744583..2745239 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2745336..2745607 + 272 - - Antitoxin
- 2745374..2745477 - 104 - - Toxin
L0Q35_RS13345 2745635..2745976 - 342 WP_000976476.1 YebY family protein -
L0Q35_RS13350 2745989..2746861 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
L0Q35_RS13355 2746865..2747239 - 375 WP_000168747.1 CopC domain-containing protein YobA -
L0Q35_RS13360 2747378..2747608 + 231 WP_000916763.1 DNA polymerase III subunit theta -
L0Q35_RS13365 2747710..2748366 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
L0Q35_RS13370 2748390..2749052 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T238281 NZ_CP093369:c2745477-2745374 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT238281 NZ_CP093369:2745336-2745607 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References