Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3304392..3304537 Replicon chromosome
Accession NC_012731
Organism Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3304399..3304501 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3304392..3304537 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP1_RS16220 3299924..3301357 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KP1_RS16225 3301473..3301712 + 240 WP_002911393.1 YebV family protein -
KP1_RS16230 3301810..3302001 + 192 WP_002911395.1 YebW family protein -
KP1_RS16235 3301998..3302651 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
KP1_RS16240 3302808..3303776 + 969 WP_014907334.1 VirK/YbjX family protein -
KP1_RS28870 3303881..3304024 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3304392..3304537 + 146 - - Antitoxin
- 3304399..3304501 - 103 - - Toxin
KP1_RS16250 3304660..3304998 - 339 WP_002911404.1 YebY family protein -
KP1_RS16255 3305015..3305884 - 870 WP_014907333.1 copper homeostasis membrane protein CopD -
KP1_RS16260 3305888..3306262 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KP1_RS16265 3306375..3306605 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KP1_RS16270 3306684..3307343 + 660 WP_002911407.1 exodeoxyribonuclease X -
KP1_RS16275 3307347..3309407 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T23826 NC_012731:c3304501-3304399 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT23826 NC_012731:3304392-3304537 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References