Detailed information of TA system TA238199

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN(toxin)
• Location: 2455308..2456023
• Replicon: chromosome
• Accession: NZ_CP093340
• Organism: Luteimonas sp. S4-F44

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: MNO14_RS11295
• Protein ID: WP_241943837.1
• Coordinates: 2455535..2456023 (+)
• Length: 163 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: MNO14_RS11290
• Protein ID: WP_241943836.1
• Coordinates: 2455308..2455538 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MNO14_RS11280 (MNO14_11280)	2451135..2454494	+	3360	WP_241943834.1	GH92 family glycosyl hydrolase	-
MNO14_RS11285 (MNO14_11285)	2454491..2455189	+	699	WP_241943835.1	basic secretory family protein	-
MNO14_RS11290 (MNO14_11290)	2455308..2455538	+	231	WP_241943836.1	hypothetical protein	Antitoxin
MNO14_RS11295 (MNO14_11295)	2455535..2456023	+	489	WP_241943837.1	hypothetical protein	Toxin
MNO14_RS11300 (MNO14_11300)	2456044..2457423	-	1380	WP_241943838.1	glutathione-disulfide reductase	-
MNO14_RS11305 (MNO14_11305)	2457420..2458667	-	1248	WP_241943839.1	FAD-dependent oxidoreductase	-
MNO14_RS11310 (MNO14_11310)	2458664..2459902	-	1239	WP_241943840.1	DUF418 domain-containing protein	-
MNO14_RS11315 (MNO14_11315)	2459973..2460452	-	480	WP_241943841.1	peptidylprolyl isomerase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain toxin (23-146)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 163 a.a.
• Molecular weight: 17452.87 Da
• Isoelectric Point: 7.3006

>T238199 WP_241943837.1 NZ_CP093340:2455535-2456023 [Luteimonas sp. S4-F44]
VTGARHRVAERAPGWPPGAPVHLLDVNVLLALLDPLHAHHDRAHDWFAQEGARGWASCPITQNGALRIMSNPRYSNPAES
VTEAAQVLAGLCAHPGHRFWPDALSLLDATHVAHDRLLTSGQVTDTYLLALAVQMGGRLASFDRRLVVDAVRGGAQALHL
LP

Nucleotide

• Length: 489 bp

>T238199 NZ_LR890270:3269536-3269709 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTAGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8156.36 Da
• Isoelectric Point: 10.3754

>AT238199 WP_241943836.1 NZ_CP093340:2455308-2455538 [Luteimonas sp. S4-F44]
MRTTLSLDDDVLAAARALAQAQGRSLGEVVSDLVRKGLTPATPPPRYRNGIPLLPARPGAERATLELVNRLRDEAP

Nucleotide

• Length: 231 bp

>AT238199 NZ_LR890270:3269212-3269508 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACCGTTGATGACTATTTCCGTCAGTTTTACAAGTAG