Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3978743..3979400 Replicon chromosome
Accession NZ_CP093334
Organism Raoultella planticola strain A2-F21

Toxin (Protein)


Gene name cptA Uniprot ID A0A2X2EG10
Locus tag MNO12_RS19210 Protein ID WP_032690815.1
Coordinates 3978990..3979400 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A514ELX1
Locus tag MNO12_RS19205 Protein ID WP_004867358.1
Coordinates 3978743..3979009 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNO12_RS19180 (MNO12_19180) 3973890..3975323 - 1434 WP_032690812.1 6-phospho-beta-glucosidase -
MNO12_RS19185 (MNO12_19185) 3975443..3976171 - 729 WP_032690813.1 MurR/RpiR family transcriptional regulator -
MNO12_RS19190 (MNO12_19190) 3976221..3976532 + 312 WP_004867365.1 N(4)-acetylcytidine aminohydrolase -
MNO12_RS19195 (MNO12_19195) 3976694..3977353 + 660 WP_004867362.1 hemolysin III family protein -
MNO12_RS19200 (MNO12_19200) 3977463..3978446 - 984 WP_047663460.1 tRNA-modifying protein YgfZ -
MNO12_RS19205 (MNO12_19205) 3978743..3979009 + 267 WP_004867358.1 FAD assembly factor SdhE Antitoxin
MNO12_RS19210 (MNO12_19210) 3978990..3979400 + 411 WP_032690815.1 protein YgfX Toxin
MNO12_RS19215 (MNO12_19215) 3979408..3979929 - 522 WP_032690816.1 flavodoxin FldB -
MNO12_RS19220 (MNO12_19220) 3980108..3981004 + 897 WP_032690817.1 site-specific tyrosine recombinase XerD -
MNO12_RS19225 (MNO12_19225) 3981027..3981740 + 714 WP_032690818.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
MNO12_RS19230 (MNO12_19230) 3981746..3983479 + 1734 WP_032696678.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16198.10 Da        Isoelectric Point: 11.3349

>T238180 WP_032690815.1 NZ_CP093334:3978990-3979400 [Raoultella planticola]
VVLWQSDLRISWRSQWFSLLLHGIVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACRGEIKLMTDSRLRWQKA
EWEIVGTPWVINSGMLLRLQDMQTRRRQHLWVAADSMDAKEWRDLRRLVLQKPAQD

Download         Length: 411 bp

>T238180 NZ_CP093334:3978990-3979400 [Raoultella planticola]
GTGGTCCTGTGGCAATCTGATTTACGCATTTCCTGGCGCTCGCAGTGGTTCTCGCTGCTGCTGCACGGCATTGTGGCGGC
TATTGTCCTGCTGATGCCCTGGCCGCTGAGCTACACACCGCTATGGCTATTGCTGCTGTCGCTGGTGGTGTTCGACAGCG
TGCGCAGCCAGCGGCGGATCCACGCCTGCCGGGGTGAAATAAAGCTGATGACCGATTCGCGTTTGCGTTGGCAAAAAGCG
GAATGGGAGATTGTCGGCACGCCGTGGGTGATTAATAGCGGGATGTTGCTGCGCCTGCAGGATATGCAAACGCGTCGCCG
CCAGCATCTGTGGGTCGCTGCAGACAGTATGGACGCCAAAGAGTGGCGAGATCTGCGCCGGTTGGTTTTACAAAAACCGG
CACAGGATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10553.05 Da        Isoelectric Point: 4.8432

>AT238180 WP_004867358.1 NZ_CP093334:3978743-3979009 [Raoultella planticola]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAQLQRMVKLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT238180 NZ_CP093334:3978743-3979009 [Raoultella planticola]
ATGGACATTACGAATAAAGCCCGCATCCACTGGGCATGCCGCAGGGGTATGCGTGAACTTGATATCTCCATCATGCCGTT
TTTCGAGTATGAGTACGATACGCTCAGCGATGAAGACAAACAGCTGTTTATCCGCCTGTTAGAAAACGACGATCCGGACC
TGTTTAACTGGCTGATGAATCATGGCGAACCGGCTGATGCACAACTGCAACGGATGGTAAAATTAATCCAGACTCGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2X2EG10

Antitoxin

Source ID Structure
AlphaFold DB A0A514ELX1

References