Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/ElaA-DUF1778
Location 61246..61982 Replicon plasmid p1
Accession NZ_CP093329
Organism Rahnella aceris strain S2-A69

Toxin (Protein)


Gene name tacT Uniprot ID H8P154
Locus tag MNO10_RS22075 Protein ID WP_014683045.1
Coordinates 61246..61725 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag MNO10_RS22080 Protein ID WP_200227549.1
Coordinates 61722..61982 (-) Length 87 a.a.

Genomic Context

MNO10_RS22070MNO10_RS22085MNO10_RS22090MNO10_RS22105MNO10_RS22055MNO10_RS22060MNO10_RS22065MNO10_RS22075MNO10_RS22080MNO10_RS22095MNO10_RS22100MNO10_RS22110
Location: 60105..61154 (1050 bp)
Type: Others
Protein ID: WP_014683046.1
Location: 62134..62475 (342 bp)
Type: Others
Protein ID: WP_241917281.1
Location: 62823..64283 (1461 bp)
Type: Others
Protein ID: WP_014683042.1
Location: 65952..66278 (327 bp)
Type: Others
Protein ID: WP_112152208.1
Location: 57380..58966 (1587 bp)
Type: Others
Protein ID: WP_013578364.1
Location: 59287..59553 (267 bp)
Type: Others
Protein ID: WP_013578404.1
Location: 59550..59795 (246 bp)
Type: Others
Protein ID: WP_013578405.1
Location: 61246..61725 (480 bp)
Type: Toxin
Protein ID: WP_014683045.1
Location: 61722..61982 (261 bp)
Type: Antitoxin
Protein ID: WP_200227549.1
Location: 64756..65535 (780 bp)
Type: Others
Protein ID: WP_200227563.1
Location: 65535..65861 (327 bp)
Type: Others
Protein ID: WP_241917282.1
Location: 66422..66762 (341 bp)
Type: Others
Protein ID: Protein_69
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MNO10_RS22055 (MNO10_22055)57380..58966-1587WP_013578364.1sensor domain-containing diguanylate cyclase-
MNO10_RS22060 (MNO10_22060)59287..59553-267WP_013578404.1Txe/YoeB family addiction module toxin-
MNO10_RS22065 (MNO10_22065)59550..59795-246WP_013578405.1type II toxin-antitoxin system Phd/YefM family antitoxin-
MNO10_RS22070 (MNO10_22070)60105..61154+1050WP_014683046.1tyrosine-type recombinase/integrase-
MNO10_RS22075 (MNO10_22075)61246..61725-480WP_014683045.1GNAT family N-acetyltransferaseToxin
MNO10_RS22080 (MNO10_22080)61722..61982-261WP_200227549.1DUF1778 domain-containing proteinAntitoxin
MNO10_RS22085 (MNO10_22085)62134..62475+342WP_241917281.1MFS transporter-
MNO10_RS22090 (MNO10_22090)62823..64283+1461WP_014683042.1sensor domain-containing diguanylate cyclase-
MNO10_RS22095 (MNO10_22095)64756..65535-780WP_200227563.1SDR family oxidoreductase-
MNO10_RS22100 (MNO10_22100)65535..65861-327WP_241917282.1nuclear transport factor 2 family protein-
MNO10_RS22105 (MNO10_22105)65952..66278+327WP_112152208.1helix-turn-helix domain-containing protein-
MNO10_RS22110 (MNO10_22110)66422..66762-341Protein_69iron-containing alcohol dehydrogenase-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..123458123458


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(26-147)

Antitoxin

Vibrio phage ICP1, Orf50

(3-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17323.02 Da        Isoelectric Point: 9.5460

>T238156 WP_014683045.1 NZ_CP093329:c61725-61246 [Rahnella aceris]
MSLQLSAPEPLTTAHILDAFGCGETTLDEWLKRRALTNHLNGASRTFVVTAHDKSVVGYYALAAGAVSHREAAGSVRRNM
PDPIPVIVLGRLAVDLRTQGVKLGSSLLQDAVLRVRSIVENTGVRALLVHALHEPAKQFYEHYGFTSSPINPMTLMLRL

Download         Length: 480 bp

>T238156 NZ_LR890240:781803-782213 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9741.18 Da        Isoelectric Point: 4.7483

>AT238156 WP_200227549.1 NZ_CP093329:c61982-61722 [Rahnella aceris]
MRDAAINLRALPEQRDLIDQAASLLGKNRSDFMLEVACERAQAILLDQVFFQLDTEKFHEFTAMLDAPHNANQGLERLMA
VKAPWA

Download         Length: 261 bp

>AT238156 NZ_LR890240:781556-781822 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBH8P154

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References