Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 124867..125462 Replicon plasmid bglu_1p
Accession NC_012723
Organism Burkholderia glumae BGR1

Toxin (Protein)


Gene name chpB Uniprot ID C5AN78
Locus tag BGLU_RS29530 Protein ID WP_012734107.1
Coordinates 124867..125217 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID C5AN79
Locus tag BGLU_RS29535 Protein ID WP_012734108.1
Coordinates 125211..125462 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BGLU_RS29505 120089..120877 - 789 WP_012734104.1 energy transducer TonB -
BGLU_RS29510 120867..123254 - 2388 WP_045678668.1 TonB-dependent receptor -
BGLU_RS29515 123556..124020 - 465 WP_012734106.1 Lrp/AsnC family transcriptional regulator -
BGLU_RS29520 124243..124464 - 222 WP_017433768.1 hypothetical protein -
BGLU_RS29525 124614..124808 - 195 WP_124837685.1 hypothetical protein -
BGLU_RS29530 124867..125217 - 351 WP_012734107.1 type II toxin-antitoxin system ChpB family toxin Toxin
BGLU_RS29535 125211..125462 - 252 WP_012734108.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BGLU_RS29540 125725..126150 - 426 WP_012734109.1 hypothetical protein -
BGLU_RS29545 126235..128070 - 1836 WP_012732711.1 site-specific integrase -
BGLU_RS29550 128073..128414 - 342 WP_012732710.1 hypothetical protein -
BGLU_RS29555 128471..128716 - 246 WP_127913916.1 hypothetical protein -
BGLU_RS35120 128713..128955 - 243 WP_124837682.1 hypothetical protein -
BGLU_RS29565 128969..129253 - 285 WP_017432347.1 hypothetical protein -
BGLU_RS29570 129641..129958 - 318 WP_148271069.1 hypothetical protein -
BGLU_RS29575 130142..130423 - 282 WP_043308454.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..133591 133591


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12389.37 Da        Isoelectric Point: 8.8909

>T23814 WP_012734107.1 NC_012723:c125217-124867 [Burkholderia glumae BGR1]
MVKRVKFERGDIVRVSLSPTVGREQQGDFRPALVLSPAAFNALGVALVAPITQGGEFARFAGFAVPLSGSGTETQGVALV
NMVRMLDLEGRGARKIERAPVEVVEDALARLQTIIE

Download         Length: 351 bp

>T23814 NC_012723:c125217-124867 [Burkholderia glumae BGR1]
ATGGTGAAGCGGGTCAAGTTCGAGCGAGGCGATATCGTGCGAGTGAGTCTGAGTCCGACGGTCGGCCGTGAGCAGCAAGG
AGATTTTCGTCCCGCGCTTGTGCTCTCTCCGGCGGCGTTTAACGCGCTGGGTGTGGCGCTCGTTGCCCCGATTACCCAGG
GCGGTGAATTCGCCCGCTTTGCAGGTTTTGCGGTTCCGCTCTCCGGTTCGGGGACGGAGACACAGGGAGTGGCACTGGTG
AACATGGTACGCATGCTCGACTTGGAAGGACGCGGCGCACGCAAGATCGAACGCGCGCCCGTCGAAGTGGTAGAGGATGC
CCTGGCCCGTCTTCAAACGATTATTGAGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8940.31 Da        Isoelectric Point: 6.2420

>AT23814 WP_012734108.1 NC_012723:c125462-125211 [Burkholderia glumae BGR1]
MELKIQKWGNSAAVRLPSVLLEQINASVGGSLNADVRPDGVLLTPARRKYALDDLVAQCDTKAPVPADMAAWGEIKPVGR
EAW

Download         Length: 252 bp

>AT23814 NC_012723:c125462-125211 [Burkholderia glumae BGR1]
ATGGAACTAAAGATTCAGAAATGGGGCAATAGCGCGGCGGTGCGTTTGCCGAGCGTATTGCTCGAACAGATCAACGCATC
GGTCGGCGGTTCGCTGAACGCGGACGTGCGGCCGGATGGGGTGCTACTGACCCCGGCCCGGCGGAAGTATGCGCTGGATG
ATCTCGTGGCTCAGTGCGACACGAAGGCGCCTGTTCCGGCCGACATGGCAGCCTGGGGCGAGATCAAGCCGGTGGGACGT
GAAGCATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A246MF70

Antitoxin

Source ID Structure
AlphaFold DB A0A246MFN5

References