Detailed information of TA system TA023812

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): slvAT/RES(toxin)
• Location: 5411..6357
• Replicon: plasmid bglu_2p
• Accession: NC_012718
• Organism: Burkholderia glumae BGR1

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: C5AN91
• Locus tag: BGLU_RS29640
• Protein ID: WP_012732709.1
• Coordinates: 5824..6357 (+)
• Length: 178 a.a.

Antitoxin (Protein)

• Gene name: slvA
• Uniprot ID: C5AN90
• Locus tag: BGLU_RS29635
• Protein ID: WP_012732708.1
• Coordinates: 5411..5827 (+)
• Length: 139 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BGLU_RS31780	1343..2422	+	1080	WP_012732706.1	ParB N-terminal domain-containing protein	-
BGLU_RS31680	2759..4090	+	1332	WP_012732707.1	hypothetical protein	-
BGLU_RS29620	4212..4538	+	327	WP_127913985.1	hypothetical protein	-
BGLU_RS29630	5078..5263	+	186	WP_017432454.1	hypothetical protein	-
BGLU_RS29635	5411..5827	+	417	WP_012732708.1	DUF2384 domain-containing protein	Antitoxin
BGLU_RS29640	5824..6357	+	534	WP_012732709.1	RES family NAD+ phosphorylase	Toxin
BGLU_RS29645	6527..6715	+	189	WP_017432455.1	hypothetical protein	-
BGLU_RS29650	7467..7751	+	285	WP_017432347.1	hypothetical protein	-
BGLU_RS35125	7765..8007	+	243	WP_124837682.1	hypothetical protein	-
BGLU_RS29660	8004..8249	+	246	WP_127913916.1	hypothetical protein	-
BGLU_RS29665	8306..8647	+	342	WP_012732710.1	hypothetical protein	-
BGLU_RS29670	8650..10485	+	1836	WP_012732711.1	site-specific integrase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..141792	141792

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (11-168)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 178 a.a.
• Molecular weight: 19101.61 Da
• Isoelectric Point: 4.7118

>T23812 WP_012732709.1 NC_012718:5824-6357 [Burkholderia glumae BGR1]
MILTPLQDITAYRMHVPKWAVAPTSGAGAAKAGGRANRIGTPALYLALEAATAVAEYQQLSPLLPPGTLVSYRVTATPVV
DFTGGYRVDLWPPLWESFFCDWRHDWFNARIEPPSWVLGDEAIASGAKGILFRSTQAAGGTNLVLFVDQLGEGDRVDVHD
PAGALPRDQASWVDSPE

Nucleotide

• Length: 534 bp

>T23812 NC_012718:5824-6357 [Burkholderia glumae BGR1]
ATGATCCTCACGCCGTTGCAGGACATCACGGCCTATCGCATGCATGTGCCCAAGTGGGCCGTCGCGCCCACCAGCGGCGC
TGGCGCGGCCAAGGCCGGGGGGCGGGCCAACCGGATCGGTACGCCAGCGTTGTACCTGGCGCTGGAGGCGGCCACCGCGG
TGGCCGAGTACCAGCAGCTGTCGCCCCTGTTGCCGCCGGGCACGTTGGTGAGCTATCGCGTCACGGCCACGCCCGTGGTC
GATTTCACCGGCGGCTACCGTGTGGATCTCTGGCCGCCCCTCTGGGAGTCGTTCTTCTGCGACTGGCGGCATGACTGGTT
CAACGCGCGCATTGAGCCGCCCAGCTGGGTACTCGGCGACGAGGCAATCGCCTCCGGCGCCAAGGGCATCCTGTTTCGCT
CGACGCAGGCCGCCGGCGGCACGAACTTGGTGCTGTTCGTCGACCAGTTGGGGGAGGGCGATCGCGTGGATGTTCACGAC
CCGGCCGGCGCCTTGCCGCGCGATCAAGCGTCGTGGGTTGACTCGCCCGAATGA

Antitoxin

Protein

• Length: 139 a.a.
• Molecular weight: 14709.55 Da
• Isoelectric Point: 6.4664

>AT23812 WP_012732708.1 NC_012718:5411-5827 [Burkholderia glumae BGR1]
MSTLAAARAPAGGPALANFDAFLSALREPDTAAPVLSARRYVAALNIDLQTLADQAHVHRNTVARAPQSASVQQFLREAI
RVIRAATDLSGDVQRALFWYRNEPLAVFDYQTAETLVSAGRADDVVRYVASLEAGAAG

Nucleotide

• Length: 417 bp

>AT23812 NC_012718:5411-5827 [Burkholderia glumae BGR1]
ATGAGCACTCTCGCAGCAGCGCGAGCCCCCGCCGGCGGTCCGGCCCTGGCAAACTTTGACGCGTTTCTCAGCGCGCTACG
CGAGCCGGACACGGCCGCTCCCGTGCTGTCGGCTCGTCGCTACGTGGCGGCCCTCAACATCGACCTGCAGACGCTCGCGG
ACCAGGCTCACGTCCATCGCAACACCGTCGCGCGCGCGCCGCAGTCAGCCAGCGTCCAGCAGTTTCTGCGCGAGGCGATT
CGCGTGATCCGAGCCGCGACGGATCTGTCGGGCGACGTTCAACGCGCGCTGTTCTGGTATCGCAACGAGCCTCTGGCCGT
CTTCGATTACCAGACGGCCGAAACGCTGGTGTCGGCAGGGCGCGCCGATGACGTTGTGCGCTATGTGGCATCGCTCGAGG
CGGGCGCCGCCGGATGA

Structures

Toxin

• AlphaFold DB: A0A2J9GLU3

Antitoxin

• AlphaFold DB: A0A2J9GLX3