Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1929855..1930000 Replicon chromosome
Accession NZ_CP093314
Organism Klebsiella pneumoniae strain HUM7199

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1929891..1929993 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1929855..1930000 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MLA24_RS09340 1924985..1927045 + 2061 WP_004148850.1 oligopeptidase B -
MLA24_RS09345 1927049..1927708 - 660 WP_032435029.1 exodeoxyribonuclease X -
MLA24_RS09350 1927787..1928017 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MLA24_RS09355 1928130..1928504 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MLA24_RS09360 1928508..1929377 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
MLA24_RS09365 1929394..1929732 + 339 WP_002911404.1 YebY family protein -
- 1929855..1930000 - 146 - - Antitoxin
- 1929891..1929993 + 103 - - Toxin
MLA24_RS09370 1930368..1930511 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MLA24_RS09375 1930616..1931584 - 969 WP_004151446.1 VirK/YbjX family protein -
MLA24_RS09380 1931741..1932394 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
MLA24_RS09385 1932391..1932582 - 192 WP_002911395.1 YebW family protein -
MLA24_RS09390 1932680..1932919 - 240 WP_002911393.1 YebV family protein -
MLA24_RS09395 1933035..1934468 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T238051 NZ_CP093314:1929891-1929993 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT238051 NZ_CP093314:c1930000-1929855 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References