238046

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 4824449..4825142 Replicon chromosome
Accession NZ_CP093313
Organism Occallatibacter riparius strain DSM 25168

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag MOP44_RS19590 Protein ID WP_260791951.1
Coordinates 4824449..4824826 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag MOP44_RS19595 Protein ID WP_260791953.1
Coordinates 4824807..4825142 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOP44_RS19565 (MOP44_19515) 4819697..4820677 - 981 WP_260791940.1 hypothetical protein -
MOP44_RS19570 (MOP44_19520) 4820947..4821306 - 360 WP_260791941.1 STAS domain-containing protein -
MOP44_RS19575 (MOP44_19525) 4821643..4822827 + 1185 WP_260791946.1 tRNA epoxyqueuosine(34) reductase QueG -
MOP44_RS19580 (MOP44_19530) 4822887..4823093 - 207 WP_260791948.1 cold-shock protein -
MOP44_RS19585 (MOP44_19535) 4823416..4824378 + 963 WP_260791949.1 YihY/virulence factor BrkB family protein -
MOP44_RS19590 (MOP44_19540) 4824449..4824826 + 378 WP_260791951.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MOP44_RS19595 (MOP44_19545) 4824807..4825142 + 336 WP_260791953.1 helix-turn-helix transcriptional regulator Antitoxin
MOP44_RS19600 (MOP44_19550) 4825147..4826355 - 1209 WP_260791955.1 beta-propeller fold lactonase family protein -
MOP44_RS19605 (MOP44_19555) 4826339..4827409 - 1071 WP_260791960.1 3-deoxy-7-phosphoheptulonate synthase -
MOP44_RS19610 (MOP44_19560) 4827827..4828675 - 849 WP_260791962.1 A24 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(17-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(40-93)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13806.00 Da        Isoelectric Point: 10.1547

>T238046 WP_260791951.1 NZ_CP093313:4824449-4824826 [Occallatibacter riparius]
VDSTEKPLYWIGSSKRDLMELPVPVRKFFGHALHFAQLGEQHEAAKPLKGFGGAGVLEIVEDSVGGTYRAVYTVKFAEAV
FVLHCFQKKSKSGIATPKKELDVISSRLKVAEAVAREIRHAKARQ

Download         Length: 378 bp

>T238046 NZ_LR890198:995435-995842 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTATTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGAAAACGGCA
ACATTTATGGCTGGCAGCTGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTACAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12197.16 Da        Isoelectric Point: 10.7115

>AT238046 WP_260791953.1 NZ_CP093313:4824807-4825142 [Occallatibacter riparius]
MPKHANKNAEVERSSGNVFADLALHDAERLKIKSGLAIEITRAVRRLGLTQQEAAARMGISQAKISGLMRGDFSNLSEHK
LMECLNRIGYNIEIKVTAGERVPGTRKLKVA

Download         Length: 336 bp

>AT238046 NZ_LR890198:995188-995454 [Escherichia coli]
ATGGACATTAATAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCAGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References