Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2213628..2214295 Replicon chromosome
Accession NZ_CP093313
Organism Occallatibacter riparius strain DSM 25168

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MOP44_RS08770 Protein ID WP_260795661.1
Coordinates 2213879..2214295 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MOP44_RS08765 Protein ID WP_260795660.1
Coordinates 2213628..2213879 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOP44_RS08745 (MOP44_08720) 2208700..2209698 - 999 WP_260795656.1 hypothetical protein -
MOP44_RS08750 (MOP44_08725) 2209795..2210439 - 645 WP_260795657.1 hypothetical protein -
MOP44_RS08755 (MOP44_08730) 2210652..2212469 - 1818 WP_260795658.1 translational GTPase TypA -
MOP44_RS08760 (MOP44_08735) 2212703..2213497 + 795 WP_260795659.1 hypothetical protein -
MOP44_RS08765 (MOP44_08740) 2213628..2213879 + 252 WP_260795660.1 hypothetical protein Antitoxin
MOP44_RS08770 (MOP44_08745) 2213879..2214295 + 417 WP_260795661.1 type II toxin-antitoxin system VapC family toxin Toxin
MOP44_RS08775 (MOP44_08750) 2214520..2215563 - 1044 WP_260795662.1 YsnF/AvaK domain-containing protein -
MOP44_RS08780 (MOP44_08755) 2215888..2218227 + 2340 WP_260795663.1 carbohydrate binding family 9 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14853.24 Da        Isoelectric Point: 6.4772

>T238043 WP_260795661.1 NZ_CP093313:2213879-2214295 [Occallatibacter riparius]
MAQRYVLDTNILSDLLKSPAGKVAQKIAGLAIAERESLATSIVVAAELRYGAAKSGSQILAERIEQLLGAIEVLPLEPDA
DGHYGIIRSQLEKTGTVIGANDLLIAAHVLAIDGILVTDNLREFKRVKGLRVENWLRA

Download         Length: 417 bp

>T238043 NZ_LR890198:180581-180688 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9468.98 Da        Isoelectric Point: 10.2843

>AT238043 WP_260795660.1 NZ_CP093313:2213628-2213879 [Occallatibacter riparius]
MSAGSAVRQVRLFKNGRSQAVRIPREFELPGNEATLRRDERGRLILEAIPRPRLLDLLATWTPLDKKDQLPEIEDLPAEP
VKL

Download         Length: 252 bp

>AT238043 NZ_LR890198:c180524-180469 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References