237985

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 353486..354039 Replicon chromosome
Accession NZ_CP093280
Organism Pseudomonas sp. T1-3-2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LZ023_RS01565 Protein ID WP_268145924.1
Coordinates 353486..353779 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LZ023_RS01570 Protein ID WP_268145925.1
Coordinates 353767..354039 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ023_RS01545 (LZ023_01545) 349308..349829 - 522 WP_268145920.1 TIGR02281 family clan AA aspartic protease -
LZ023_RS01550 (LZ023_01550) 349826..350818 - 993 WP_268145921.1 esterase-like activity of phytase family protein -
LZ023_RS01555 (LZ023_01555) 350818..352722 - 1905 WP_268145922.1 DNA topoisomerase IV subunit B -
LZ023_RS01560 (LZ023_01560) 352761..353369 - 609 WP_268145923.1 YqiA/YcfP family alpha/beta fold hydrolase -
LZ023_RS01565 (LZ023_01565) 353486..353779 - 294 WP_268145924.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LZ023_RS01570 (LZ023_01570) 353767..354039 - 273 WP_268145925.1 ribbon-helix-helix protein, CopG family Antitoxin
LZ023_RS01575 (LZ023_01575) 354249..355064 - 816 WP_268145926.1 3',5'-cyclic-AMP phosphodiesterase -
LZ023_RS01580 (LZ023_01580) 355281..355733 - 453 WP_158157214.1 DUF1249 domain-containing protein -
LZ023_RS01585 (LZ023_01585) 355724..356335 - 612 WP_158157212.1 NUDIX domain-containing protein -
LZ023_RS01590 (LZ023_01590) 356550..357296 + 747 WP_268145927.1 DUF3298 domain-containing protein -
LZ023_RS01595 (LZ023_01595) 357265..358551 - 1287 WP_268145929.1 putative hydroxymethylpyrimidine transporter CytX -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-39)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11041.89 Da        Isoelectric Point: 9.5446

>T237985 WP_268145924.1 NZ_CP093280:c353779-353486 [Pseudomonas sp. T1-3-2]
VPRLIVTQRAVQGLERCRKFLLEKGIQTAGRAALAIERQFSLVQMSPVMGRPFSLDPELRELIIEFGDSGYVALYRFEPK
ADAVYILAFRHQKEAGY

Download         Length: 294 bp

>T237985 NZ_LR883965:c2408284-2407934 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10451.52 Da        Isoelectric Point: 4.6115

>AT237985 WP_268145925.1 NZ_CP093280:c354039-353767 [Pseudomonas sp. T1-3-2]
VATSIKIDDDLKDRIQHLAALRQRTAHWLMREAITEYVQREEARESFKQEAQESWAAYQETGLHLDGEQVSAWLKTWAAD
EKAEAPECHD

Download         Length: 273 bp

>AT237985 NZ_LR883965:c2408529-2408278 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGCGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References