Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2479355..2480012 Replicon chromosome
Accession NZ_CP093260
Organism Moellerella wisconsensis strain W17-3

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MNY68_RS11060 Protein ID WP_047255277.1
Coordinates 2479355..2479765 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag MNY68_RS11065 Protein ID WP_047255278.1
Coordinates 2479746..2480012 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNY68_RS11040 (MNY68_11040) 2474619..2476352 - 1734 WP_241540453.1 single-stranded-DNA-specific exonuclease RecJ -
MNY68_RS11045 (MNY68_11045) 2476361..2477053 - 693 WP_047255274.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
MNY68_RS11050 (MNY68_11050) 2477078..2477989 - 912 WP_047255275.1 site-specific tyrosine recombinase XerD -
MNY68_RS11055 (MNY68_11055) 2478210..2478728 + 519 WP_047255276.1 flavodoxin FldB -
MNY68_RS11060 (MNY68_11060) 2479355..2479765 - 411 WP_047255277.1 protein YgfX Toxin
MNY68_RS11065 (MNY68_11065) 2479746..2480012 - 267 WP_047255278.1 FAD assembly factor SdhE Antitoxin
MNY68_RS11070 (MNY68_11070) 2480273..2481265 + 993 WP_241500861.1 tRNA-modifying protein YgfZ -
MNY68_RS11075 (MNY68_11075) 2481283..2481903 + 621 WP_241540454.1 HD domain-containing protein -
MNY68_RS11080 (MNY68_11080) 2482100..2484979 - 2880 WP_241540455.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15525.49 Da        Isoelectric Point: 10.3270

>T237951 WP_047255277.1 NZ_CP093260:c2479765-2479355 [Moellerella wisconsensis]
VVLWKSNLSISWMAQLFSTCVHCVLGLVLLLAPWPTGNSIIWLPLLMVTIASWAKSQKNINKYKGIIVLTNGNKVQWKKN
EWSIITPPWCTRFGILLTLSALQGKPRKIKLWIAADAISEDDWRNLNQLLLQYPDI

Download         Length: 411 bp

>T237951 NZ_LR883013:c45629-45423 [Escherichia coli]
ATGAAGTACCTTAACACTACTGATTGTAGCCTCTTCCTTGCAGAGAGGTCAAAGTTTATGACGAAATATGCCCTTATAGG
GTTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTTATGTGAACTGAATATTCACAGGG
GAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10681.11 Da        Isoelectric Point: 5.1391

>AT237951 WP_047255278.1 NZ_CP093260:c2480012-2479746 [Moellerella wisconsensis]
MDIDNKARIHWACRRGMRELDISIMPFFEHEYDGLNDNEKHQFIRLLECADPDLFNWLMNHGRPDDDELYHMIKLIQQRN
KDRGPVEI

Download         Length: 267 bp

>AT237951 NZ_LR883013:45616-45677 [Escherichia coli]
TTAAGGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References