237946

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3216075..3216549 Replicon chromosome
Accession NZ_CP093255
Organism Moellerella wisconsensis strain W1

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag MNY70_RS14105 Protein ID WP_241540606.1
Coordinates 3216075..3216341 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag MNY70_RS14110 Protein ID WP_047257105.1
Coordinates 3216325..3216549 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNY70_RS14085 (MNY70_14085) 3211394..3212308 - 915 WP_047257110.1 ribonuclease Z -
MNY70_RS14090 (MNY70_14090) 3212338..3213939 - 1602 WP_241543354.1 RNA repair transcriptional activator RtcR -
MNY70_RS14095 (MNY70_14095) 3214223..3214438 + 216 WP_241543355.1 hypothetical protein -
MNY70_RS14100 (MNY70_14100) 3214460..3215587 + 1128 WP_047257107.1 slipin family protein -
MNY70_RS14105 (MNY70_14105) 3216075..3216341 - 267 WP_241540606.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MNY70_RS14110 (MNY70_14110) 3216325..3216549 - 225 WP_047257105.1 TraY domain-containing protein Antitoxin
MNY70_RS18645 3216739..3216867 + 129 WP_269430907.1 hypothetical protein -
MNY70_RS14115 (MNY70_14115) 3217017..3217394 - 378 WP_241501090.1 hypothetical protein -
MNY70_RS14120 (MNY70_14120) 3217372..3217707 - 336 WP_241544675.1 hypothetical protein -
MNY70_RS14125 (MNY70_14125) 3217732..3218418 - 687 WP_241544676.1 hypothetical protein -
MNY70_RS14130 (MNY70_14130) 3218730..3218948 - 219 WP_241544677.1 hypothetical protein -
MNY70_RS14135 (MNY70_14135) 3219186..3219950 - 765 WP_241544678.1 hypothetical protein -
MNY70_RS14140 (MNY70_14140) 3220055..3221148 - 1094 Protein_2750 IS3 family transposase -
MNY70_RS18650 3221161..3221403 + 243 WP_277627823.1 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3220055..3220858 803


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Relaxosome protein TraY

(4-45)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10404.04 Da        Isoelectric Point: 9.5211

>T237946 WP_241540606.1 NZ_CP093255:c3216341-3216075 [Moellerella wisconsensis]
MVWTINYSERALKSLRKMDKQSARRIVDFMGLRIAALDDPRQLGKSLKGELGEFWRYRVGDYRILCEIRDDELVILAATT
GHRREIYE

Download         Length: 267 bp

>T237946 NZ_LR883012:2753240-2753347 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8470.51 Da        Isoelectric Point: 4.5201

>AT237946 WP_047257105.1 NZ_CP093255:c3216549-3216325 [Moellerella wisconsensis]
MLAIRLSDDIETRLESLAKQTGRTKTFYAREAILTHLEDLEDYYLSAETIAKIRSGEELIHSSEEVRKTLGLDD

Download         Length: 225 bp

>AT237946 NZ_LR883012:c2753193-2753127 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References