Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2556672..2557329 Replicon chromosome
Accession NZ_CP093255
Organism Moellerella wisconsensis strain W1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MNY70_RS11365 Protein ID WP_047255277.1
Coordinates 2556672..2557082 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag MNY70_RS11370 Protein ID WP_047255278.1
Coordinates 2557063..2557329 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNY70_RS11345 (MNY70_11345) 2551936..2553669 - 1734 WP_241543231.1 single-stranded-DNA-specific exonuclease RecJ -
MNY70_RS11350 (MNY70_11350) 2553678..2554370 - 693 WP_047255274.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
MNY70_RS11355 (MNY70_11355) 2554395..2555306 - 912 WP_047255275.1 site-specific tyrosine recombinase XerD -
MNY70_RS11360 (MNY70_11360) 2555527..2556045 + 519 WP_047255276.1 flavodoxin FldB -
MNY70_RS11365 (MNY70_11365) 2556672..2557082 - 411 WP_047255277.1 protein YgfX Toxin
MNY70_RS11370 (MNY70_11370) 2557063..2557329 - 267 WP_047255278.1 FAD assembly factor SdhE Antitoxin
MNY70_RS11375 (MNY70_11375) 2557590..2558582 + 993 WP_241544565.1 tRNA-modifying protein YgfZ -
MNY70_RS11380 (MNY70_11380) 2558600..2559220 + 621 WP_241500862.1 HD domain-containing protein -
MNY70_RS11385 (MNY70_11385) 2559392..2562271 - 2880 WP_241544566.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15525.49 Da        Isoelectric Point: 10.3270

>T237943 WP_047255277.1 NZ_CP093255:c2557082-2556672 [Moellerella wisconsensis]
VVLWKSNLSISWMAQLFSTCVHCVLGLVLLLAPWPTGNSIIWLPLLMVTIASWAKSQKNINKYKGIIVLTNGNKVQWKKN
EWSIITPPWCTRFGILLTLSALQGKPRKIKLWIAADAISEDDWRNLNQLLLQYPDI

Download         Length: 411 bp

>T237943 NZ_LR883012:2413084-2414406 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10681.11 Da        Isoelectric Point: 5.1391

>AT237943 WP_047255278.1 NZ_CP093255:c2557329-2557063 [Moellerella wisconsensis]
MDIDNKARIHWACRRGMRELDISIMPFFEHEYDGLNDNEKHQFIRLLECADPDLFNWLMNHGRPDDDELYHMIKLIQQRN
KDRGPVEI

Download         Length: 267 bp

>AT237943 NZ_LR883012:2412818-2413084 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References