237939

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3195518..3195992 Replicon chromosome
Accession NZ_CP093249
Organism Moellerella wisconsensis strain W18-2

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag MNY64_RS14045 Protein ID WP_241540606.1
Coordinates 3195518..3195784 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag MNY64_RS14050 Protein ID WP_047257105.1
Coordinates 3195768..3195992 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNY64_RS14025 (MNY64_14030) 3190837..3191751 - 915 WP_047257110.1 ribonuclease Z -
MNY64_RS14030 (MNY64_14035) 3191781..3193382 - 1602 WP_241543354.1 RNA repair transcriptional activator RtcR -
MNY64_RS14035 (MNY64_14040) 3193666..3193881 + 216 WP_241543355.1 hypothetical protein -
MNY64_RS14040 (MNY64_14045) 3193903..3195030 + 1128 WP_047257107.1 slipin family protein -
MNY64_RS14045 (MNY64_14050) 3195518..3195784 - 267 WP_241540606.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MNY64_RS14050 (MNY64_14055) 3195768..3195992 - 225 WP_047257105.1 TraY domain-containing protein Antitoxin
MNY64_RS18355 3196182..3196310 + 129 WP_269430907.1 hypothetical protein -
MNY64_RS14055 (MNY64_14060) 3196842..3197810 - 969 WP_241543356.1 T6SS immunity protein Tli4 family protein -
MNY64_RS14060 (MNY64_14065) 3197906..3199630 - 1725 WP_241543357.1 acetyltransferase -
MNY64_RS14065 (MNY64_14070) 3199780..3200850 - 1071 WP_241543358.1 T6SS immunity protein Tli4 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Relaxosome protein TraY

(4-45)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10404.04 Da        Isoelectric Point: 9.5211

>T237939 WP_241540606.1 NZ_CP093249:c3195784-3195518 [Moellerella wisconsensis]
MVWTINYSERALKSLRKMDKQSARRIVDFMGLRIAALDDPRQLGKSLKGELGEFWRYRVGDYRILCEIRDDELVILAATT
GHRREIYE

Download         Length: 267 bp

>T237939 NZ_LR883012:1060196-1060531 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8470.51 Da        Isoelectric Point: 4.5201

>AT237939 WP_047257105.1 NZ_CP093249:c3195992-3195768 [Moellerella wisconsensis]
MLAIRLSDDIETRLESLAKQTGRTKTFYAREAILTHLEDLEDYYLSAETIAKIRSGEELIHSSEEVRKTLGLDD

Download         Length: 225 bp

>AT237939 NZ_LR883012:1059948-1060196 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References