237932

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3155785..3156259 Replicon chromosome
Accession NZ_CP093245
Organism Moellerella wisconsensis strain W51

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag MNY72_RS13990 Protein ID WP_047257106.1
Coordinates 3155785..3156051 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag MNY72_RS13995 Protein ID WP_047257105.1
Coordinates 3156035..3156259 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNY72_RS13970 (MNY72_13960) 3151104..3152018 - 915 WP_047257110.1 ribonuclease Z -
MNY72_RS13975 (MNY72_13965) 3152048..3153649 - 1602 WP_241542032.1 RNA repair transcriptional activator RtcR -
MNY72_RS13980 (MNY72_13970) 3153933..3154148 + 216 WP_047257108.1 hypothetical protein -
MNY72_RS13985 (MNY72_13975) 3154170..3155297 + 1128 WP_047257107.1 slipin family protein -
MNY72_RS13990 (MNY72_13980) 3155785..3156051 - 267 WP_047257106.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MNY72_RS13995 (MNY72_13985) 3156035..3156259 - 225 WP_047257105.1 TraY domain-containing protein Antitoxin
MNY72_RS17565 3156449..3156577 + 129 WP_269430907.1 hypothetical protein -
MNY72_RS14000 (MNY72_13990) 3156727..3157104 - 378 WP_241501090.1 hypothetical protein -
MNY72_RS14005 (MNY72_13995) 3157082..3157420 - 339 WP_241542033.1 hypothetical protein -
MNY72_RS14010 (MNY72_14000) 3157445..3158131 - 687 WP_241542034.1 hypothetical protein -
MNY72_RS14015 (MNY72_14005) 3158443..3158661 - 219 WP_241542035.1 hypothetical protein -
MNY72_RS14020 (MNY72_14010) 3158899..3159675 - 777 WP_241542036.1 hypothetical protein -
MNY72_RS14025 (MNY72_14015) 3159878..3160096 - 219 WP_241542037.1 hypothetical protein -
MNY72_RS14030 (MNY72_14020) 3160334..3161098 - 765 WP_241542038.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Relaxosome protein TraY

(4-45)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10416.09 Da        Isoelectric Point: 9.5211

>T237932 WP_047257106.1 NZ_CP093245:c3156051-3155785 [Moellerella wisconsensis]
MVWTINYSERALKSLRKMDKQSARRIVDFMGLRIAALDDPRQLGKSLKGELGEFWRYRVGDYRILCEIRDDELVILAATI
GHRREIYE

Download         Length: 267 bp

>T237932 NZ_LR883009:49278-49439 [Escherichia coli]
ATGAAACTACCGGGAAACGCCCTTATCTGGTGCGTATTAATCGTGTGCTGCACGTTGTTGATATTCACACTCCTGACCCG
GAATCGCCTGTGCGAAGTCCGGCTGAAGGACGGATACAGGGAAGTTACGGCAACAATGGCTTACGAATCCGGCGGTAAGT
AG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8470.51 Da        Isoelectric Point: 4.5201

>AT237932 WP_047257105.1 NZ_CP093245:c3156259-3156035 [Moellerella wisconsensis]
MLAIRLSDDIETRLESLAKQTGRTKTFYAREAILTHLEDLEDYYLSAETIAKIRSGEELIHSSEEVRKTLGLDD

Download         Length: 225 bp

>AT237932 NZ_LR883009:c49212-49032 [Escherichia coli]
GCCTCGTGGGTTAATGAAAATTAACTACGGGGCTTTCTGCTTTCTGCCACACAACACGGTAACAAACCACCTTCACGTCA
TGAGGCAGAAAGCCTCAAGCGCCGGGCACATCATAGCCCATATACCAGCACGCTGACCACATTCACTTTCCCTGAAAATA
ATCCGGTCGTTCAGCCAGTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References