Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | Hha-TomB/- |
| Location | 2898849..2899488 | Replicon | chromosome |
| Accession | NZ_CP093245 | ||
| Organism | Moellerella wisconsensis strain W51 | ||
Toxin (Protein)
| Gene name | Hha | Uniprot ID | - |
| Locus tag | MNY72_RS12980 | Protein ID | WP_269430900.1 |
| Coordinates | 2899264..2899488 (+) | Length | 75 a.a. |
Antitoxin (Protein)
| Gene name | TomB | Uniprot ID | - |
| Locus tag | MNY72_RS12975 | Protein ID | WP_047256412.1 |
| Coordinates | 2898849..2899217 (+) | Length | 123 a.a. |
Genomic Context
Location: 2894868..2895335 (468 bp)
Type: Others
Protein ID: WP_047256408.1
Type: Others
Protein ID: WP_047256408.1
Location: 2896089..2896844 (756 bp)
Type: Others
Protein ID: WP_047256410.1
Type: Others
Protein ID: WP_047256410.1
Location: 2896916..2898271 (1356 bp)
Type: Others
Protein ID: WP_047256411.1
Type: Others
Protein ID: WP_047256411.1
Location: 2898849..2899217 (369 bp)
Type: Antitoxin
Protein ID: WP_047256412.1
Type: Antitoxin
Protein ID: WP_047256412.1
Location: 2899264..2899488 (225 bp)
Type: Toxin
Protein ID: WP_269430900.1
Type: Toxin
Protein ID: WP_269430900.1
Location: 2901106..2901969 (864 bp)
Type: Others
Protein ID: WP_241501033.1
Type: Others
Protein ID: WP_241501033.1
Location: 2894050..2894811 (762 bp)
Type: Others
Protein ID: WP_047256407.1
Type: Others
Protein ID: WP_047256407.1
Location: 2895338..2896054 (717 bp)
Type: Others
Protein ID: WP_047256409.1
Type: Others
Protein ID: WP_047256409.1
Location: 2900248..2900709 (462 bp)
Type: Others
Protein ID: WP_241541987.1
Type: Others
Protein ID: WP_241541987.1
Location: 2903034..2904317 (1284 bp)
Type: Others
Protein ID: WP_047256416.1
Type: Others
Protein ID: WP_047256416.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MNY72_RS12950 (MNY72_12940) | 2894050..2894811 | - | 762 | WP_047256407.1 | DNA polymerase III subunit epsilon | - |
| MNY72_RS12955 (MNY72_12945) | 2894868..2895335 | + | 468 | WP_047256408.1 | ribonuclease HI | - |
| MNY72_RS12960 (MNY72_12950) | 2895338..2896054 | - | 717 | WP_047256409.1 | methyltransferase domain-containing protein | - |
| MNY72_RS12965 (MNY72_12955) | 2896089..2896844 | + | 756 | WP_047256410.1 | hydroxyacylglutathione hydrolase | - |
| MNY72_RS12970 (MNY72_12960) | 2896916..2898271 | + | 1356 | WP_047256411.1 | murein transglycosylase D | - |
| MNY72_RS12975 (MNY72_12965) | 2898849..2899217 | + | 369 | WP_047256412.1 | Hha toxicity modulator TomB | Antitoxin |
| MNY72_RS12980 (MNY72_12970) | 2899264..2899488 | + | 225 | WP_269430900.1 | HHA domain-containing protein | Toxin |
| MNY72_RS12990 (MNY72_12980) | 2900248..2900709 | - | 462 | WP_241541987.1 | YbaY family lipoprotein | - |
| MNY72_RS12995 (MNY72_12985) | 2901106..2901969 | + | 864 | WP_241501033.1 | acyl-CoA thioesterase II | - |
| MNY72_RS13000 (MNY72_12990) | 2903034..2904317 | - | 1284 | WP_047256416.1 | ammonium transporter AmtB | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 75 a.a. Molecular weight: 8977.32 Da Isoelectric Point: 5.8622
>T237931 WP_269430900.1 NZ_CP093245:2899264-2899488 [Moellerella wisconsensis]
MNERQENMTKTDYLMRLRKCTTIETLERVIEKNKYELSDDELELFFSAADHRLAELTMNKLYDKIPASVWKYVR
MNERQENMTKTDYLMRLRKCTTIETLERVIEKNKYELSDDELELFFSAADHRLAELTMNKLYDKIPASVWKYVR
Download Length: 225 bp
>T237931 NZ_LR883008:128487-128648 [Escherichia coli]
ATGAAACTACCGGGAAACGCCCTTATCTGGTGCGTATTAATCGTGTGCTGCACGTTGTTAATATTCACACTCCTGACCCG
GAATCGTCTGTGCGAAGTCCGGCTGAAGGACGGATACAGGGAGGTTACGGCAAGTTTGGCTTACGAATCCAGCGGTAAGT
AG
ATGAAACTACCGGGAAACGCCCTTATCTGGTGCGTATTAATCGTGTGCTGCACGTTGTTAATATTCACACTCCTGACCCG
GAATCGTCTGTGCGAAGTCCGGCTGAAGGACGGATACAGGGAGGTTACGGCAAGTTTGGCTTACGAATCCAGCGGTAAGT
AG
Antitoxin
Download Length: 123 a.a. Molecular weight: 14371.20 Da Isoelectric Point: 4.5817
>AT237931 WP_047256412.1 NZ_CP093245:2898849-2899217 [Moellerella wisconsensis]
MDEYSPRYYDTAELKYLCDSLNNDAILSLHKTKTHWINDLSSQQSTNLNELIEHVAAFFWKFKIKYPSERLVISLVDEYL
DETYNLFGSPLITLNEFSDWQKMNTHLIDELNNDLKCSVAKL
MDEYSPRYYDTAELKYLCDSLNNDAILSLHKTKTHWINDLSSQQSTNLNELIEHVAAFFWKFKIKYPSERLVISLVDEYL
DETYNLFGSPLITLNEFSDWQKMNTHLIDELNNDLKCSVAKL
Download Length: 369 bp
>AT237931 NZ_LR883008:128235-128434 [Escherichia coli]
CCCGTGAACTGGCTGAACGACCGGATTATTTTCAGGGAAAGTGAGTGTGGTCAGTGTGCAGGTATATGGGCTATGATGTG
CCCGGCGCTTGAGGCTTTCTGCCTCATGACGTGAAGGTGGTTTGTTACCGTGTTGTGTGGCAGAAGGCAGAAAGCCCCGT
AGTTAATTTTTCATTAACCCACGAGGCCCCCTGTATGTCT
CCCGTGAACTGGCTGAACGACCGGATTATTTTCAGGGAAAGTGAGTGTGGTCAGTGTGCAGGTATATGGGCTATGATGTG
CCCGGCGCTTGAGGCTTTCTGCCTCATGACGTGAAGGTGGTTTGTTACCGTGTTGTGTGGCAGAAGGCAGAAAGCCCCGT
AGTTAATTTTTCATTAACCCACGAGGCCCCCTGTATGTCT