237923

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3177538..3178012 Replicon chromosome
Accession NZ_CP093242
Organism Moellerella wisconsensis strain W65

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag MNY66_RS13835 Protein ID WP_047257106.1
Coordinates 3177538..3177804 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag MNY66_RS13840 Protein ID WP_047257105.1
Coordinates 3177788..3178012 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNY66_RS13815 (MNY66_13815) 3172857..3173771 - 915 WP_047257110.1 ribonuclease Z -
MNY66_RS13820 (MNY66_13820) 3173801..3175402 - 1602 WP_241501089.1 RNA repair transcriptional activator RtcR -
MNY66_RS13825 (MNY66_13825) 3175686..3175901 + 216 WP_047257108.1 hypothetical protein -
MNY66_RS13830 (MNY66_13830) 3175923..3177050 + 1128 WP_047257107.1 slipin family protein -
MNY66_RS13835 (MNY66_13835) 3177538..3177804 - 267 WP_047257106.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MNY66_RS13840 (MNY66_13840) 3177788..3178012 - 225 WP_047257105.1 TraY domain-containing protein Antitoxin
MNY66_RS17945 3178202..3178330 + 129 WP_269430907.1 hypothetical protein -
MNY66_RS13845 (MNY66_13845) 3178480..3178857 - 378 WP_241501090.1 hypothetical protein -
MNY66_RS13850 (MNY66_13850) 3178835..3179173 - 339 WP_241501091.1 hypothetical protein -
MNY66_RS13855 (MNY66_13855) 3179198..3179884 - 687 WP_241501092.1 hypothetical protein -
MNY66_RS13860 (MNY66_13860) 3180196..3180414 - 219 WP_241501093.1 hypothetical protein -
MNY66_RS13865 (MNY66_13865) 3180652..3181422 - 771 WP_241501094.1 hypothetical protein -
MNY66_RS13870 (MNY66_13870) 3181625..3181843 - 219 WP_053907512.1 hypothetical protein -
MNY66_RS13875 (MNY66_13875) 3182081..3182845 - 765 WP_241501095.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Relaxosome protein TraY

(4-45)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10416.09 Da        Isoelectric Point: 9.5211

>T237923 WP_047257106.1 NZ_CP093242:c3177804-3177538 [Moellerella wisconsensis]
MVWTINYSERALKSLRKMDKQSARRIVDFMGLRIAALDDPRQLGKSLKGELGEFWRYRVGDYRILCEIRDDELVILAATI
GHRREIYE

Download         Length: 267 bp

>T237923 NZ_LR883006:3894245-3894523 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATGCTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8470.51 Da        Isoelectric Point: 4.5201

>AT237923 WP_047257105.1 NZ_CP093242:c3178012-3177788 [Moellerella wisconsensis]
MLAIRLSDDIETRLESLAKQTGRTKTFYAREAILTHLEDLEDYYLSAETIAKIRSGEELIHSSEEVRKTLGLDD

Download         Length: 225 bp

>AT237923 NZ_LR883006:3893982-3894242 [Escherichia coli]
ATGGCTGCTAACGCATTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References