Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2499742..2500399 Replicon chromosome
Accession NZ_CP093242
Organism Moellerella wisconsensis strain W65

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MNY66_RS11015 Protein ID WP_047255277.1
Coordinates 2499742..2500152 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag MNY66_RS11020 Protein ID WP_047255278.1
Coordinates 2500133..2500399 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNY66_RS10995 (MNY66_10995) 2495005..2496738 - 1734 WP_241500860.1 single-stranded-DNA-specific exonuclease RecJ -
MNY66_RS11000 (MNY66_11000) 2496747..2497439 - 693 WP_047255274.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
MNY66_RS11005 (MNY66_11005) 2497464..2498375 - 912 WP_047255275.1 site-specific tyrosine recombinase XerD -
MNY66_RS11010 (MNY66_11010) 2498596..2499114 + 519 WP_047255276.1 flavodoxin FldB -
MNY66_RS11015 (MNY66_11015) 2499742..2500152 - 411 WP_047255277.1 protein YgfX Toxin
MNY66_RS11020 (MNY66_11020) 2500133..2500399 - 267 WP_047255278.1 FAD assembly factor SdhE Antitoxin
MNY66_RS11025 (MNY66_11025) 2500660..2501652 + 993 WP_241500861.1 tRNA-modifying protein YgfZ -
MNY66_RS11030 (MNY66_11030) 2501670..2502290 + 621 WP_241500862.1 HD domain-containing protein -
MNY66_RS11035 (MNY66_11035) 2502462..2505341 - 2880 WP_241500863.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15525.49 Da        Isoelectric Point: 10.3270

>T237920 WP_047255277.1 NZ_CP093242:c2500152-2499742 [Moellerella wisconsensis]
VVLWKSNLSISWMAQLFSTCVHCVLGLVLLLAPWPTGNSIIWLPLLMVTIASWAKSQKNINKYKGIIVLTNGNKVQWKKN
EWSIITPPWCTRFGILLTLSALQGKPRKIKLWIAADAISEDDWRNLNQLLLQYPDI

Download         Length: 411 bp

>T237920 NZ_LR883006:c2894724-2894569 [Escherichia coli]
ATGAAGCAGCAAAAGGCGATGTTAATCGCCCTTATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAA
AGACCTCTGCGAGGTACGAATCCGAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10681.11 Da        Isoelectric Point: 5.1391

>AT237920 WP_047255278.1 NZ_CP093242:c2500399-2500133 [Moellerella wisconsensis]
MDIDNKARIHWACRRGMRELDISIMPFFEHEYDGLNDNEKHQFIRLLECADPDLFNWLMNHGRPDDDELYHMIKLIQQRN
KDRGPVEI

Download         Length: 267 bp

>AT237920 NZ_LR883006:2894736-2894794 [Escherichia coli]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTACATGTGTTCAGCATGGATTGAGCCTCA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References