Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) CapRel-ATcapRel/-
Location 4807979..4808937 Replicon chromosome
Accession NZ_CP093238
Organism Gordonia alkanivorans strain GH-1

Toxin (Protein)


Gene name capRel Uniprot ID -
Locus tag MND02_RS21955 Protein ID WP_241548844.1
Coordinates 4808227..4808937 (-) Length 237 a.a.

Antitoxin (Protein)


Gene name ATcapRel Uniprot ID -
Locus tag MND02_RS21950 Protein ID WP_241548843.1
Coordinates 4807979..4808230 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MND02_RS21895 4803339..4803644 + 306 WP_241548832.1 hypothetical protein -
MND02_RS21900 4803641..4803943 + 303 WP_241548833.1 transcriptional regulator -
MND02_RS21905 4804190..4804537 + 348 WP_241548834.1 helix-turn-helix domain-containing protein -
MND02_RS21910 4804534..4804761 + 228 WP_241548835.1 hypothetical protein -
MND02_RS21915 4804758..4805573 + 816 WP_241548836.1 hypothetical protein -
MND02_RS21920 4805589..4805960 + 372 WP_241548837.1 DUF2190 family protein -
MND02_RS21925 4806130..4806480 + 351 WP_241548838.1 hypothetical protein -
MND02_RS21930 4806477..4806797 + 321 WP_241548839.1 HNH endonuclease signature motif containing protein -
MND02_RS21935 4806945..4807289 + 345 WP_241548840.1 hypothetical protein -
MND02_RS21940 4807324..4807581 + 258 WP_241548841.1 hypothetical protein -
MND02_RS21945 4807583..4807909 + 327 WP_241548842.1 hypothetical protein -
MND02_RS21950 4807979..4808230 - 252 WP_241548843.1 hypothetical protein Antitoxin
MND02_RS21955 4808227..4808937 - 711 WP_241548844.1 RelA/SpoT domain-containing protein Toxin
MND02_RS21960 4809389..4810090 - 702 WP_241548845.1 hypothetical protein -
MND02_RS21965 4810078..4810383 - 306 WP_241548846.1 hypothetical protein -
MND02_RS21975 4811030..4813054 + 2025 WP_241548847.1 cytochrome c oxidase assembly protein -
MND02_RS21980 4813068..4813646 - 579 WP_241548848.1 chorismate mutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(70-168)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 237 a.a.        Molecular weight: 26780.80 Da        Isoelectric Point: 10.2738

>T237889 WP_241548844.1 NZ_CP093238:c4808937-4808227 [Gordonia alkanivorans]
MPPADIPSKNRVNRAGDTLRAFSELLSEGRVDEVREALEVLFAWRTSHGKPLQTATMGLRSRVQTEGCQVEVSQRLKRVP
TIIDKLYREPGMNLARMADIGGCRAVLNSIDEVRRVEKRLCKKRPPKIYHDYIAEPKPSGYRGVHVISVYHERLIEVQLR
TRVMHEWAFMVERVTGQIGTDVKSGRGPQAVRDWFQAVSEAMALEEQGLTVHETLATRVAQLRATAQPYLRAGRNQ

Download         Length: 711 bp

>T237889 NZ_LR882997:3918880-3919422 [Escherichia coli]
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9301.52 Da        Isoelectric Point: 5.5235

>AT237889 WP_241548843.1 NZ_CP093238:c4808230-4807979 [Gordonia alkanivorans]
MTQIKHFLLVFDHARAELLDIQEFGSDARSAMRAYAEKEREHLKAGDSIEIVLIGSDSLDTVRLTHANYFDGTVAVSKYF
AGI

Download         Length: 252 bp

>AT237889 NZ_LR882997:3918585-3918896 [Escherichia coli]
ATGCCTGGAAAAACAGCCACTCTACCCGATGTCGATAAAACGCTGAAAAATGCGCGGGTCGAACTCAAAACTAGTCCCGA
CGCCAAAAACAAACTTCGTGAAGCTGCGCAAGCCGTTGGGGTAGATTTAAGCGCTTTTATTTTGAGCGCTGCTATGGAAC
GCGCCGAAAGTGTGCTTGATAACCAACGTCGCCGTGAGCTTTCGAATCAAAGCTGGGAACTGATGAACCAACTCATCGCT
GAACCTGCTCAACCGACGCTCGCCCTCAAGGCGTTAATGAAAAGGAAAAACAGCGATGGTCGACAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References