Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 1650735..1651297 Replicon chromosome
Accession NZ_CP093238
Organism Gordonia alkanivorans strain GH-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MND02_RS07470 Protein ID WP_006360630.1
Coordinates 1650735..1651025 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MND02_RS07475 Protein ID WP_035753144.1
Coordinates 1651022..1651297 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MND02_RS07455 1647511..1648272 - 762 WP_035753140.1 IclR family transcriptional regulator -
MND02_RS07460 1648423..1649697 + 1275 WP_035753142.1 aldolase/citrate lyase family protein -
MND02_RS07465 1649754..1650566 + 813 WP_241549264.1 bifunctional allantoicase/(S)-ureidoglycine aminohydrolase -
MND02_RS07470 1650735..1651025 - 291 WP_006360630.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MND02_RS07475 1651022..1651297 - 276 WP_035753144.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MND02_RS07480 1651541..1651696 - 156 Protein_1471 type II toxin-antitoxin system Phd/YefM family antitoxin -
MND02_RS07485 1651777..1652499 - 723 WP_035753146.1 aspartate/glutamate racemase family protein -
MND02_RS07490 1652520..1654073 - 1554 WP_035753147.1 NCS1 family nucleobase:cation symporter-1 -
MND02_RS07495 1654323..1655717 + 1395 WP_006360625.1 allantoinase AllB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10875.35 Da        Isoelectric Point: 10.2270

>T237888 WP_006360630.1 NZ_CP093238:c1651025-1650735 [Gordonia alkanivorans]
MNDAPTDSPAPYRVEVASPARRDLQRLPSRIVHAVIEFISGPLAENPHRLSKPLRDDLGGLHSARRGDYRVLLRIDDPNH
TIVVVRIDHRAHAYRT

Download         Length: 291 bp

>T237888 NZ_LR882997:3884902-3885120 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9750.93 Da        Isoelectric Point: 4.6221

>AT237888 WP_035753144.1 NZ_CP093238:c1651297-1651022 [Gordonia alkanivorans]
MTTVPLGEAKDKLSALIDSAETTHDIITITKHGKPAAVLMSADDLESLHETIYWLSRAGLRDDVATADAEYAAGHTVSID
DLRAEHGLPPK

Download         Length: 276 bp

>AT237888 NZ_LR882997:3884502-3884876 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References