Detailed information of TA system TA237813

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /HTH_26(antitoxin)
• Location: 1071424..1072223
• Replicon: chromosome
• Accession: NZ_CP093217
• Organism: Staphylococcus edaphicus strain CCM 8731

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: MNY58_RS05095
• Protein ID: WP_099088986.1
• Coordinates: 1071424..1071888 (-)
• Length: 155 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: MNY58_RS05100
• Protein ID: WP_099088987.1
• Coordinates: 1071900..1072223 (-)
• Length: 108 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MNY58_RS05075 (MNY58_05075)	1068910..1069296	+	387	WP_099088983.1	aspartate 1-decarboxylase	-
MNY58_RS05085 (MNY58_05085)	1069832..1070878	-	1047	WP_099088984.1	site-specific integrase	-
MNY58_RS05090 (MNY58_05090)	1070936..1071400	-	465	WP_099088985.1	hypothetical protein	-
MNY58_RS05095 (MNY58_05095)	1071424..1071888	-	465	WP_099088986.1	ImmA/IrrE family metallo-endopeptidase	Toxin
MNY58_RS05100 (MNY58_05100)	1071900..1072223	-	324	WP_099088987.1	helix-turn-helix transcriptional regulator	Antitoxin
MNY58_RS05105 (MNY58_05105)	1072394..1072612	+	219	WP_099088988.1	BetR domain protein	-
MNY58_RS05110 (MNY58_05110)	1072644..1072937	+	294	WP_099088989.1	DUF771 domain-containing protein	-
MNY58_RS05115 (MNY58_05115)	1072950..1073123	+	174	WP_161940530.1	hypothetical protein	-
MNY58_RS05120 (MNY58_05120)	1073192..1073455	+	264	WP_099088990.1	DUF1108 family protein	-
MNY58_RS05125 (MNY58_05125)	1073452..1073676	+	225	WP_099088991.1	DUF2483 family protein	-
MNY58_RS05130 (MNY58_05130)	1073666..1074358	+	693	WP_099088992.1	AAA family ATPase	-
MNY58_RS05135 (MNY58_05135)	1074472..1075764	+	1293	WP_249740177.1	DEAD/DEAH box helicase	-
MNY58_RS05140 (MNY58_05140)	1075786..1076358	+	573	WP_099088993.1	DUF669 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1069832..1115447	45615

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• IrrE N-terminal-like domain (29-119)

Antitoxin

• Cro/C1-type helix-turn-helix domain (5-60)

Sequences

Toxin

Protein

• Length: 155 a.a.
• Molecular weight: 18170.00 Da
• Isoelectric Point: 6.2910

>T237813 WP_099088986.1 NZ_CP093217:c1071888-1071424 [Staphylococcus edaphicus]
MGSFEQMLIDNDDVKIKETNILPYELSGLTLDKMILLNTNNKHVHKLEVLAEELAHRKITYGDIRDQSKILNRKFELKAR
RLGCEMVITLDGIIDAFHEGICNLHEMACYFEVSNNYVLKAIEHYKMKYGLDVYYKGYVIKFEPLQVYEHHNWE

Nucleotide

• Length: 465 bp

>T237813 NZ_LR882967:c3219103-3218762 [Planktothrix pseudagardhii]
TTGGTAAATCAATCCTATATTCCTGATAGGGGACATATTGTCAAATTAAATTTTAATCCTACTCAAGGACATGAACAAAA
GGGCTTAAGACCCGCTTTCGTTATTTCACCTTACGAATATAATGTTAAGAACTCCTTAGCTTTATTTATGCCAATTACAG
CACAGGTAAAAGGCTATCCTTTTGAAGTGAGTCTTCCTTCAGAGTTAACAACTTATGGCGTTATTTTGGTAGACCATATC
AAAAGTTTGGATTATAAAGTTCGTTTAATTCAGTTTATTGAAATAGTACCCGAAGATGTAATTCAAGAAGTTCAGGCAAA
AATAGAGGTACTCATCTTCTAA

Antitoxin

Protein

• Length: 108 a.a.
• Molecular weight: 12307.04 Da
• Isoelectric Point: 5.0194

>AT237813 WP_099088987.1 NZ_CP093217:c1072223-1071900 [Staphylococcus edaphicus]
MKPDIKKRRLELNLTLEEVGNIVGVGKSTVRKWETGDIENMKRDKIVKLANALKVSPSYIMGFEEEPKDEPTTGFETIAA
HLDGELTEEQWKKVIEYARFIQDNDNK

Nucleotide

• Length: 324 bp

>AT237813 NZ_LR882967:c3219339-3219097 [Planktothrix pseudagardhii]
ATGGTAACTAATGTAGCGAAGTGGGGGAATAGTCTAGCGGTTCGCATCCCTCAAAATATTGCTCAAGCGATTCAAATTTC
CGAAGGTTCACAAGTTACTTTTAGTGTAGAAAATGGAACGATTGTGATTAAACCCAGTAATCGTAAACGTTATTCTCTTG
AAGAACTTGTGAGCCAAATCACTCCTGAAAATTGCCACACTGAAACAGACACAGGACTCGCCGTGGGGAATGAAGTTTGG
TAA