Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 1000684..1001245 Replicon chromosome
Accession NZ_CP093215
Organism Mycoplasma mycoides subsp. capri strain HN-A

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MNF30_RS04185 Protein ID WP_265510446.1
Coordinates 1000684..1000980 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MNF30_RS04190 Protein ID WP_265510447.1
Coordinates 1000973..1001245 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNF30_RS04170 (MNF30_04165) 996357..997635 + 1279 Protein_796 IS3 family transposase -
MNF30_RS04175 (MNF30_04170) 997741..999348 + 1608 WP_265510444.1 LppA family lipoprotein -
MNF30_RS04180 (MNF30_04175) 999385..1000266 - 882 WP_265510445.1 Cof-type HAD-IIB family hydrolase -
MNF30_RS04185 (MNF30_04180) 1000684..1000980 - 297 WP_265510446.1 type II toxin-antitoxin system YafQ family toxin Toxin
MNF30_RS04190 (MNF30_04185) 1000973..1001245 - 273 WP_265510447.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MNF30_RS04195 (MNF30_04190) 1001521..1002030 - 510 WP_265510448.1 hypothetical protein -
MNF30_RS04200 (MNF30_04195) 1002295..1002393 - 99 WP_265510449.1 BspA family leucine-rich repeat surface protein -
MNF30_RS04205 (MNF30_04200) 1002831..1005923 - 3093 WP_265510450.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11424.33 Da        Isoelectric Point: 10.0664

>T237810 WP_265510446.1 NZ_CP093215:c1000980-1000684 [Mycoplasma mycoides subsp. capri]
MTKYKIVTTKFKKDLKLAKKQNKDLNKLDYVINILTQGKELDAKYRDHSLTGIYKGYRECHIDPDLLIYKKDDDKIVITM
LRLGSHSNLFEKQRNY

Download         Length: 297 bp

>T237810 NZ_LR882967:c2273603-2273217 [Planktothrix pseudagardhii]
ATGAATTCTTTTCTGTTAGATACTCATACTTTTATTTGGTTATCGGAAAATGATCCTAATTTACCTGATAGCCTAAGAGA
GATGATTGATATAGCGGATCATGTTTATCTGAGTATTGCCAGTCTTTGGGAAATTGCGATTAAGTTAAATTTGGGTAAAT
TGTCATTACAACAAAGTTATAAAACCATTGAAGATAAGCTTGAAAATTCAGATATTCTTTTGCTCCCTATTATGTTTATT
GATACGTTACAAATTTGTAATCTACCCTTACATCATCGAGATCCTTTTGATCGAATGTTAATCGCTCAAGCCATCAATAG
ATCCCTAATTTTAATTAGCAGAGATATCAAGTTTGATGCTTATCCTATTCAGAGATTATGGGATTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10233.69 Da        Isoelectric Point: 4.6437

>AT237810 WP_265510447.1 NZ_CP093215:c1001245-1000973 [Mycoplasma mycoides subsp. capri]
MKTTNLNVRIDKEVKLDAEAIFNELGLSTSAAINMFFKATIRNNSLPFSTKLDTPNKETLLAMKEAEELLKDPNTKYYSS
FKELLETLDD

Download         Length: 273 bp

>AT237810 NZ_LR882967:c2273830-2273600 [Planktothrix pseudagardhii]
ATGAATATTGATACGGAAATCCTACAAATGGTTGGGATAATGCCAGAATCTCTAAAACAAGAGCTTCTACATTATGCTAA
CTATCTTATGGAAAACTACTCCCAAAAGACTCCCTCAGAGCAGCCCCCTGTTAAAAAACGTCGCTCAGGAATATTACAAG
GGACTTTTGTTTTACCTCTATCTGATGATTTTGATGAACCTTTAGAAGATTTTAAGGAATATATGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References