Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 843790..844319 Replicon chromosome
Accession NZ_CP093202
Organism Staphylococcus epidermidis strain TSM-31

Toxin (Protein)


Gene name mazF Uniprot ID Q5HME7
Locus tag MNU47_RS03900 Protein ID WP_001829891.1
Coordinates 843957..844319 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID Q5HME6
Locus tag MNU47_RS03895 Protein ID WP_001829931.1
Coordinates 843790..843960 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13497.65 Da        Isoelectric Point: 9.9522

>T237786 WP_001829891.1 NZ_CP093202:843957-844319 [Staphylococcus epidermidis]
MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKKKYKLDKDSVILLEQIR
TLDKKRLKEKLTFLSESKMIEVDNALDISLGLNNFDHHKS

Download         Length: 363 bp

>T237786 NZ_LR882944:c3246141-3245869 [Planktothrix agardhii]
ATGTATAGCTTTGAGTATGACGACAATAAAAGTCGAACCAACCAACAAAAACACGGCATAGACTTCATCGAAGCCCAACA
ACTTTGGCAAGACGATGACTTGTTGGAAATTCAGGCTACAAGCGAAACAGAATCGCGTTTTTTAGCCATTGGCAAACTGA
AGCAAAAACACTGGACAGCCGTTATCACTTACAGATTAGAAAATATCCGAATTATTTCCGTCCGCCGTTCCCGTCCCAAT
GAGGTTATATGGTATGAAAGCCGAAGAATTTGA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6289.92 Da        Isoelectric Point: 4.1920

>AT237786 WP_001829931.1 NZ_CP093202:843790-843960 [Staphylococcus epidermidis]
MLSFNQNRNHSLEQSLKEGYAQMADLNLSLATEAFPIECEACDCNESHLISNSKNE

Download         Length: 171 bp

>AT237786 NZ_LR882944:c3245888-3245664 [Planktothrix agardhii]
ATGAAAGCCGAAGAATTTGACGCAAAATTTGACACAGGTGAAGACCTCACCGAATTTATGGATTTCTCGACCGCCAGACG
ACCCAACCGAGAAAAACAAAAAATAGAACTCAATTTACCCCTCTGGATGATTCGCCAACTCGAAGCCGAAGCTCAAAAAC
AGGGTATTTCTCCCCAAACCTTTTTAGAAAACTATTTAGCCGAAAATCTTGCCCCTGTTAGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G7HWR0

Antitoxin

Source ID Structure
AlphaFold DB A0A0N1EF65

References