Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1968701..1968846 Replicon chromosome
Accession NZ_CP093151
Organism Klebsiella pneumoniae strain CY814036

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1968737..1968839 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1968701..1968846 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MMZ10_RS09520 1963831..1965891 + 2061 WP_004899137.1 oligopeptidase B -
MMZ10_RS09525 1965895..1966554 - 660 WP_002911407.1 exodeoxyribonuclease X -
MMZ10_RS09530 1966633..1966863 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MMZ10_RS09535 1966976..1967350 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MMZ10_RS09540 1967354..1968223 + 870 WP_004899136.1 copper homeostasis membrane protein CopD -
MMZ10_RS09545 1968240..1968578 + 339 WP_002911404.1 YebY family protein -
- 1968701..1968846 - 146 - - Antitoxin
- 1968737..1968839 + 103 - - Toxin
MMZ10_RS09550 1969214..1969357 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MMZ10_RS09555 1969462..1970430 - 969 WP_004151446.1 VirK/YbjX family protein -
MMZ10_RS09560 1970587..1971240 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
MMZ10_RS09565 1971237..1971428 - 192 WP_002911395.1 YebW family protein -
MMZ10_RS09570 1971526..1971765 - 240 WP_002911393.1 YebV family protein -
MMZ10_RS09575 1971881..1973314 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T237701 NZ_CP093151:1968737-1968839 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT237701 NZ_CP093151:c1968846-1968701 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References