Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) paaR-paaA-parE/ParE(toxin)
Location 1801484..1801959 Replicon chromosome
Accession NZ_CP093046
Organism Bartonella krasnovii strain 84B_2

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag MNL00_RS07545 Protein ID WP_120121236.1
Coordinates 1801484..1801771 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag MNL00_RS07550 Protein ID WP_241439170.1
Coordinates 1801771..1801959 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNL00_RS07520 (MNL00_07520) 1796581..1797723 - 1143 WP_120121231.1 OpgC domain-containing protein -
MNL00_RS07525 (MNL00_07525) 1797999..1798661 + 663 WP_120121233.1 thiamine phosphate synthase -
MNL00_RS07530 (MNL00_07530) 1799267..1800043 + 777 WP_241436038.1 nucleotide-binding protein -
MNL00_RS07535 (MNL00_07535) 1800495..1800896 + 402 WP_120122708.1 helix-turn-helix transcriptional regulator -
MNL00_RS07540 (MNL00_07540) 1800903..1801124 + 222 WP_148255698.1 hypothetical protein -
MNL00_RS07545 (MNL00_07545) 1801484..1801771 - 288 WP_120121236.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MNL00_RS07550 (MNL00_07550) 1801771..1801959 - 189 WP_241439170.1 antitoxin Antitoxin
MNL00_RS07555 (MNL00_07555) 1802464..1802832 + 369 WP_241439171.1 helix-turn-helix transcriptional regulator -
MNL00_RS07560 (MNL00_07560) 1803155..1803567 + 413 Protein_1467 hypothetical protein -
MNL00_RS07565 (MNL00_07565) 1804771..1805814 + 1044 WP_120121242.1 tetratricopeptide repeat protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11097.98 Da        Isoelectric Point: 10.1866

>T237652 WP_120121236.1 NZ_CP093046:c1801771-1801484 [Bartonella krasnovii]
MLPVVWLSSARDDLRQILTYIARENPSAARRMKRFLETSVLPLAEHPYLYRQSERILGLREIIAHPNYLILYRVAANQIE
IVAVVHARREFPTSL

Download         Length: 288 bp

>T237652 NZ_LR882498:3815153-3815563 [Mycobacterium tuberculosis variant microti]
GTGATCTATATGGACACCTCGGCCCTGACTAAGCTGCTCATCTCCGAGCCCGAGACGACCGAACTGCGGACATGGCTGAC
CGCGCAAAGCGGCCAGGGCGAGGACGCGGCGACAAGCACCCTTGGCCGGGTCGAGTTGATGAGAGTCGTTGCCCGATACG
GACAACCAGGCCAAACTGAGCGTGCGCGTTACCTACTCGACGGGCTCGACATCCTCCCGCTCACCGAACCGGTGATCGGT
CTAGCTGAAACGATCGGACCGGCCACCCTACGTTCTCTCGACGCGATTCACCTCGCGGCCGCAGCCCAGATCAAGCGGGA
ACTGACAGCCTTCGTCACCTACGACCACCGATTGTTGAGCGGATGCCGTGAGGTCGGCTTCGTCACCGCCTCACCCGGCG
CAGTCCGGTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7053.99 Da        Isoelectric Point: 4.3167

>AT237652 WP_241439170.1 NZ_CP093046:c1801959-1801771 [Bartonella krasnovii]
MKNTLSPFISEFETVEQESSHTAWLRDKVAISLANLSPPIPHDEVMAEMDVIISQLENEQKK

Download         Length: 189 bp

>AT237652 NZ_LR882498:3814878-3815156 [Mycobacterium tuberculosis variant microti]
GTGGAGGCAATCGGAATCCGAGAACTAAGACAGCACGCATCGCGATACCTCGCCCGGGTTGAAGCCGGCGAGGAACTTGG
CGTCACCAACAAAGGAAGACTTGTGGCCCGACTCATCCCGGTGCAGGCCGCGGAGCGTTCTCGCGAAGCCCTGATTGAAT
CAGGTGTCCTGATTCCGGCTCGTCGTCCACAAAACCTTCTCGACGTCACCGCCGAACCGGCGCGCGGCCGCAAGCGCACC
CTGTCCGATGTTCTCAACGAAATGCGCGACGAGCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References