Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) paaR-paaA-parE/ParE(toxin)
Location 1795633..1796108 Replicon chromosome
Accession NZ_CP093043
Organism Bartonella krasnovii strain 51A_7

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag MNL03_RS07690 Protein ID WP_120121236.1
Coordinates 1795633..1795920 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag MNL03_RS07695 Protein ID WP_120121238.1
Coordinates 1795920..1796108 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNL03_RS07665 (MNL03_07665) 1791242..1791760 - 519 WP_120121229.1 DUF1465 family protein -
MNL03_RS07670 (MNL03_07670) 1791961..1793103 - 1143 WP_120121231.1 OpgC domain-containing protein -
MNL03_RS07675 (MNL03_07675) 1793379..1794041 + 663 WP_120121233.1 thiamine phosphate synthase -
MNL03_RS07680 (MNL03_07680) 1794644..1795045 + 402 WP_120122708.1 helix-turn-helix transcriptional regulator -
MNL03_RS07685 (MNL03_07685) 1795052..1795273 + 222 WP_148255698.1 hypothetical protein -
MNL03_RS07690 (MNL03_07690) 1795633..1795920 - 288 WP_120121236.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MNL03_RS07695 (MNL03_07695) 1795920..1796108 - 189 WP_120121238.1 antitoxin Antitoxin
MNL03_RS07700 (MNL03_07700) 1796610..1796978 + 369 WP_241439948.1 helix-turn-helix transcriptional regulator -
MNL03_RS07705 (MNL03_07705) 1797359..1797728 + 370 Protein_1497 helix-turn-helix transcriptional regulator -
MNL03_RS07710 (MNL03_07710) 1798051..1798463 + 413 Protein_1498 hypothetical protein -
MNL03_RS07715 (MNL03_07715) 1799667..1800710 + 1044 WP_120121242.1 tetratricopeptide repeat protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11097.98 Da        Isoelectric Point: 10.1866

>T237644 WP_120121236.1 NZ_CP093043:c1795920-1795633 [Bartonella krasnovii]
MLPVVWLSSARDDLRQILTYIARENPSAARRMKRFLETSVLPLAEHPYLYRQSERILGLREIIAHPNYLILYRVAANQIE
IVAVVHARREFPTSL

Download         Length: 288 bp

>T237644 NZ_LR882498:c3131950-3131066 [Mycobacterium tuberculosis variant microti]
GTGGCCGGTCTGACCCGTGCGCTCGTTGCGCGTCACGCTCTTGGTCGGGCCGAGGCATACGACGCCGCTCTGCTCGACGT
CGCCCAGGACCACCTGCTGTACCTGCTGTCGCAGACCGTCCAGTTCGGCGATAACCGCCTGGTGTTCAAAGGCGGTACCA
GCTTACGGAAGTGCCGGCTGGGCAACGTCGGGCGGTTCTCCACTGATCTGGACTTCAGCGCGCCCGACGATGAGGTCGTG
CTGGAGGTGTGCGAGCTGATCGACGGCGCCCGTGTCGGCGGCTTCGAATTCGGCGTGCAGAGCACACGAGGCGACGGCCG
GCATTGGCAGTTGCGGGTGCGGCACACGGAATTGGGCGAGCCCCGGATCGTCGCCAGCGTCGAGTTCGCACGGCGGCCGT
TGGCTTTGCCGTCTGAGCTGCTCGCATTCATCCAGTTGCCGATCCATAAGGCTTACGGTTTTGGGCTGCCGACACTGCCG
GTCGTGGCAGAAGCGGAAGCCTGCGCAGAGAAACTCGCGCGGTACCGCCGCGTTGCGCTGGCACGGGACCTGTACGACCT
GAACCACTTCGCCTCGCGAACGATTGACGAACCGCTCGTGCGGCGGCTGTGGGTGCTCAAGGTGTGGGGTGATGTCGTCG
ATGACCGGCGCGGCACCCGGCCACTACGCGTCGAAGACGTCCTCGCCGCCCGCAGCGAGCACGACTTCCAGCCCGACTCG
ATCGGCGTGCTGACCCGTCCTGTCGCTATGGCTGCCTGGGAAGCTCGCGTTCGGAAGCGATTTGCGTTCCTCACTGACCT
CGACGCCGACGAGCAGCGGTGGGCCGCCTGCGACGAACGGCACCGCCGCGAAGTGGAGAACGCGCTGGCGGTGCTGCGGT
CCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7068.01 Da        Isoelectric Point: 4.3167

>AT237644 WP_120121238.1 NZ_CP093043:c1796108-1795920 [Bartonella krasnovii]
MKNTLSPFISEFETIEQESSHTAWLRDKVAISLANLSPPIPHDEVMAEMDVIISQLENEQKK

Download         Length: 189 bp

>AT237644 NZ_LR882498:c3132840-3131953 [Mycobacterium tuberculosis variant microti]
GTGGTGAGCCCAGCCGGCGCCGATCGGCGCATCCCCACGTGGGCGTCACGGGTGGTGTCCGGCCTCGCTCGCGATCGGCC
CGTAGTCGTCACGAAAGAGGATCTGACGCAACGGCTTACAGAGGCTGGGTGTGGACGCGACCCCGACTCCGCCATCCGCG
AACTGCGCCGCATTGGGTGGCTGGTCCAACTGCCGGTGAAAGGCACCTGGGCATTCATTCCCCCCGGCGAGGCCGCCATC
TCGGACCCGTATCTACCGCTGCGCTCGTGGCTGGCCCGTGACCAGAACGCGGGCTTCATGCTGGCCGGTGCATCCGCAGC
GTGGCACCTCGGATACCTGGACCGCCAACCCGACGGCCGCATCCCGATCTGGCTGCCGCCGGCCAAAAGGCTGCCCGACG
GCCTAGCATCGTATGTGTCCGTCGTGCGCATCCCCTGGAACGCGGCGGACACCGCACTGCTGGCTCCGCGTCCCGCGTTG
CTGGTCCGGCGGCGGCTCGACCTCGTCGCGTGGGCGACCGGGTTACCGGCGCTAGGACCAGAAGCATTACTTGTGCAAAT
CGCCACGCGCCCGGCCTCGTTCGGGCCGTGGGCCGACCTTGTCCCCCACCTTGACGACCTCGTCGCCGACTGCAGTGACG
AGCGTCTGGAGCGTCTACTGTCGGGCCGGCCGACATCGGCCTGGCAGCGTGCAAGCTACCTGCTGGACTCGGGCGGTGAA
CCGGCACGAGGCCAGGCGCTGCTGGCCAAGCGGCACACCGAAGTGATGCCGGTGACTCGATTCACCACCGCGCACAGCCG
CGACCGTGGCGAGAGTGTCTGGGCTCCCGAGTATCAGCTTGTCGACGAGCTCGTCGTACCGCTGCTGCGCGTGATCGGCA
AGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References