Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-DUF971
Location 737490..738063 Replicon chromosome
Accession NZ_CP093040
Organism Bartonella krasnovii strain 75A_1b

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag MNL06_RS02895 Protein ID WP_120122373.1
Coordinates 737755..738063 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag MNL06_RS02890 Protein ID WP_120122374.1
Coordinates 737490..737774 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNL06_RS02870 (MNL06_02870) 732915..734933 + 2019 WP_241436961.1 portal protein -
MNL06_RS02875 (MNL06_02875) 734946..735830 + 885 WP_120122377.1 hypothetical protein -
MNL06_RS02880 (MNL06_02880) 735924..737048 + 1125 WP_120122376.1 N4-gp56 family major capsid protein -
MNL06_RS02885 (MNL06_02885) 737074..737454 + 381 WP_120122375.1 hypothetical protein -
MNL06_RS02890 (MNL06_02890) 737490..737774 - 285 WP_120122374.1 putative addiction module antidote protein Antitoxin
MNL06_RS02895 (MNL06_02895) 737755..738063 - 309 WP_120122373.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MNL06_RS02900 (MNL06_02900) 738138..738845 + 708 WP_120122787.1 hypothetical protein -
MNL06_RS02905 (MNL06_02905) 738847..740307 + 1461 WP_120122372.1 hypothetical protein -
MNL06_RS02910 (MNL06_02910) 740307..740732 + 426 WP_120122371.1 hypothetical protein -
MNL06_RS02915 (MNL06_02915) 740734..741654 + 921 WP_241440832.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 710794..795713 84919


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-91)

Antitoxin

Uncharacterized protein HI1420

(13-92)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11857.83 Da        Isoelectric Point: 9.7095

>T237631 WP_120122373.1 NZ_CP093040:c738063-737755 [Bartonella krasnovii]
MILIHKTIEFDTWLKKLKDKSVKAIILQRVVRLKQGLFGDVKFFHGIGELRIHYGAGYRIYFTQKGSDFILLLCGGDKST
QQRDIEQALKLKEEYSDENNPI

Download         Length: 309 bp

>T237631 NZ_LR882498:2327689-2328099 [Mycobacterium tuberculosis variant microti]
TTGGCTGAGCCACGGCGAGGAGACCTTTGGCTGGTCAGCCTCGGCGCCGCTCGCGCGGGTGAGCCCGGCAAGCATCGGCC
CGCGGTGGTCGTTTCCGTGGACGAGCTACTCACCGGAATCGACGACGAACTCGTTGTCGTCGTGCCGGTGTCAAGCTCGC
GCTCCCGCACCCCACTCCGGCCACCTGTCGCGCCCTCAGAAGGTGTAGCTGCCGATAGCGTCGCGGTGTGCCGCGGCGTC
CGCGCGGTCGCTCGTGCCCGACTCGTGGAGCGACTCGGCGCCCTCAAACCCGCCACGATGCGCGCAATCGAAAACGCCCT
GACCCTGATCCTCGGCCTCCCGACGGGACCTGAGCGCGGCGAGGCGGCGACCCATTCTCCCGTACGGTGGACGGGTGGCC
GGGACCCGTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10191.69 Da        Isoelectric Point: 9.6249

>AT237631 WP_120122374.1 NZ_CP093040:c737774-737490 [Bartonella krasnovii]
MKITPFKPEEYLKDIESQKIFLNEALKTGDAAHIADALGIVARAQNMSALAKETNRERSGLYRSLSKTGDPKLSTLVAVL
SALNLQLSVQSSTS

Download         Length: 285 bp

>AT237631 NZ_LR882498:2327463-2327696 [Mycobacterium tuberculosis variant microti]
ATGTCTACATCCACGACGATTAGGGTTTCAACCCAGACTCGGGATCGTCTGGCCGCCCAAGCCCGCGAACGGGGAATCTC
GATGTCGGCTCTGCTCACCGAACTGGCCGCCCAGGCCGAGCGCCAGGCAATCTTCCGCGCCGAACGCGAGGCCTCGCACG
CCGAGACGACCACCCAGGCAGTCCGCGACGAGGACCGCGAGTGGGAGGGCACGGTAGGCGACGGCCTTGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References