Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) paaR-paaA-parE/ParE(toxin)
Location 1835751..1836226 Replicon chromosome
Accession NZ_CP093037
Organism Bartonella krasnovii strain B1_2_M1

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag MNL09_RS07920 Protein ID WP_120121236.1
Coordinates 1835751..1836038 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag MNL09_RS07925 Protein ID WP_120121238.1
Coordinates 1836038..1836226 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNL09_RS07900 (MNL09_07850) 1831358..1831878 - 521 Protein_1522 DUF1465 family protein -
MNL09_RS07905 (MNL09_07855) 1832079..1833221 - 1143 WP_120121231.1 OpgC domain-containing protein -
MNL09_RS07910 (MNL09_07860) 1833497..1834159 + 663 WP_120121233.1 thiamine phosphate synthase -
MNL09_RS07915 (MNL09_07865) 1834762..1835163 + 402 WP_120122708.1 helix-turn-helix transcriptional regulator -
MNL09_RS07920 (MNL09_07870) 1835751..1836038 - 288 WP_120121236.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MNL09_RS07925 (MNL09_07875) 1836038..1836226 - 189 WP_120121238.1 antitoxin Antitoxin
MNL09_RS07930 (MNL09_07880) 1836695..1837096 + 402 WP_277623407.1 helix-turn-helix transcriptional regulator -
MNL09_RS07935 (MNL09_07885) 1837419..1837831 + 413 Protein_1529 hypothetical protein -
MNL09_RS07940 (MNL09_07890) 1839035..1840078 + 1044 WP_120121242.1 tetratricopeptide repeat protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11097.98 Da        Isoelectric Point: 10.1866

>T237623 WP_120121236.1 NZ_CP093037:c1836038-1835751 [Bartonella krasnovii]
MLPVVWLSSARDDLRQILTYIARENPSAARRMKRFLETSVLPLAEHPYLYRQSERILGLREIIAHPNYLILYRVAANQIE
IVAVVHARREFPTSL

Download         Length: 288 bp

>T237623 NZ_LR882498:1970029-1970277 [Mycobacterium tuberculosis variant microti]
ATGGTGATCGATACCTCTGCGCTGGTCGCGATGCTCAACGATGAACCCGAGGCGCAACGGTTCGAGATAGCCGTGGCAGC
AGACCACGTTTGGCTGATGTCGACGGCGTCATATCCGGAGATGGCGACCGTGATCGAAACACGCTTCGGGGAACCGGGGG
GACGTGAACCCAAGGTCAGCGGCCAGCCTCTCCTCTATACGGGTGACGATTTCGCATGTATCGATATTCGCGCGGTTCTC
GCCGGCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7068.01 Da        Isoelectric Point: 4.3167

>AT237623 WP_120121238.1 NZ_CP093037:c1836226-1836038 [Bartonella krasnovii]
MKNTLSPFISEFETIEQESSHTAWLRDKVAISLANLSPPIPHDEVMAEMDVIISQLENEQKK

Download         Length: 189 bp

>AT237623 NZ_LR882498:1969817-1970029 [Mycobacterium tuberculosis variant microti]
ATGGAATTGGCGGCTCGAATGGGCGAGACTTTGACACAAGCGGTCGTAGTTGCAGTGCGGGAGCAACTGGCCCGCCGGAC
CGGGCGCACCAGATCCATTTCGCTACGCGAGGAGTTGGCCGCCATTGGCCGGCGCTGCGCGGCCTTACCGGTGCTCGACA
CCCGAGCCGCGGACACGATTCTCGGCTACGACGAGCGCGGGTTGCCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References