Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PumAB/upstrm_HI1419-DUF971 |
| Location | 916099..916672 | Replicon | chromosome |
| Accession | NZ_CP093037 | ||
| Organism | Bartonella krasnovii strain B1_2_M1 | ||
Toxin (Protein)
| Gene name | PumA | Uniprot ID | - |
| Locus tag | MNL09_RS03965 | Protein ID | WP_120122373.1 |
| Coordinates | 916364..916672 (-) | Length | 103 a.a. |
Antitoxin (Protein)
| Gene name | PumB | Uniprot ID | - |
| Locus tag | MNL09_RS03960 | Protein ID | WP_120122374.1 |
| Coordinates | 916099..916383 (-) | Length | 95 a.a. |
Genomic Context
Location: 911860..913542 (1683 bp)
Type: Others
Protein ID: WP_241436388.1
Type: Others
Protein ID: WP_241436388.1
Location: 913555..914439 (885 bp)
Type: Others
Protein ID: WP_241441153.1
Type: Others
Protein ID: WP_241441153.1
Location: 914533..915657 (1125 bp)
Type: Others
Protein ID: WP_120122376.1
Type: Others
Protein ID: WP_120122376.1
Location: 915683..916063 (381 bp)
Type: Others
Protein ID: WP_120122375.1
Type: Others
Protein ID: WP_120122375.1
Location: 916747..917454 (708 bp)
Type: Others
Protein ID: WP_120122787.1
Type: Others
Protein ID: WP_120122787.1
Location: 917456..918916 (1461 bp)
Type: Others
Protein ID: WP_277623601.1
Type: Others
Protein ID: WP_277623601.1
Location: 918916..919341 (426 bp)
Type: Others
Protein ID: WP_277623602.1
Type: Others
Protein ID: WP_277623602.1
Location: 919343..920185 (843 bp)
Type: Others
Protein ID: WP_277623603.1
Type: Others
Protein ID: WP_277623603.1
Location: 920208..921524 (1317 bp)
Type: Others
Protein ID: WP_277623604.1
Type: Others
Protein ID: WP_277623604.1
Location: 916099..916383 (285 bp)
Type: Antitoxin
Protein ID: WP_120122374.1
Type: Antitoxin
Protein ID: WP_120122374.1
Location: 916364..916672 (309 bp)
Type: Toxin
Protein ID: WP_120122373.1
Type: Toxin
Protein ID: WP_120122373.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MNL09_RS03940 (MNL09_03930) | 911860..913542 | + | 1683 | WP_241436388.1 | phage portal protein | - |
| MNL09_RS03945 (MNL09_03935) | 913555..914439 | + | 885 | WP_241441153.1 | hypothetical protein | - |
| MNL09_RS03950 (MNL09_03940) | 914533..915657 | + | 1125 | WP_120122376.1 | N4-gp56 family major capsid protein | - |
| MNL09_RS03955 (MNL09_03945) | 915683..916063 | + | 381 | WP_120122375.1 | hypothetical protein | - |
| MNL09_RS03960 (MNL09_03950) | 916099..916383 | - | 285 | WP_120122374.1 | putative addiction module antidote protein | Antitoxin |
| MNL09_RS03965 (MNL09_03955) | 916364..916672 | - | 309 | WP_120122373.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| MNL09_RS03970 (MNL09_03960) | 916747..917454 | + | 708 | WP_120122787.1 | hypothetical protein | - |
| MNL09_RS03975 (MNL09_03965) | 917456..918916 | + | 1461 | WP_277623601.1 | hypothetical protein | - |
| MNL09_RS03980 (MNL09_03970) | 918916..919341 | + | 426 | WP_277623602.1 | hypothetical protein | - |
| MNL09_RS03985 (MNL09_03975) | 919343..920185 | + | 843 | WP_277623603.1 | hypothetical protein | - |
| MNL09_RS03990 (MNL09_03980) | 920208..921524 | + | 1317 | WP_277623604.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 838176..951249 | 113073 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 a.a. Molecular weight: 11857.83 Da Isoelectric Point: 9.7095
>T237622 WP_120122373.1 NZ_CP093037:c916672-916364 [Bartonella krasnovii]
MILIHKTIEFDTWLKKLKDKSVKAIILQRVVRLKQGLFGDVKFFHGIGELRIHYGAGYRIYFTQKGSDFILLLCGGDKST
QQRDIEQALKLKEEYSDENNPI
MILIHKTIEFDTWLKKLKDKSVKAIILQRVVRLKQGLFGDVKFFHGIGELRIHYGAGYRIYFTQKGSDFILLLCGGDKST
QQRDIEQALKLKEEYSDENNPI
Download Length: 309 bp
>T237622 NZ_LR882498:c1949466-1949077 [Mycobacterium tuberculosis variant microti]
GTGATCGTGTTGGACGCCTCGGCGGCCGTCGAGCTCATGCTCACGACGCCGGCGGGTGCGGCGGTCGCCCGGCGCTTGCG
GGGCGAAACCGTGCACGCCCCTGCACATTTCGATGTCGAGGTGATCGGGGCGATACGTCAAGCGGTCGTGCGTCAGCTGA
TCAGCGATCATGAAGGACTCGTCGTGGTTGTCAACTTCCTTAGCCTGCCCGTTCGGCGTTGGCCGTTAAAGCCATTCACC
CAGCGTGCCTATCAACTTCGGTCCACTCATACCGTGGCCGATGGAGCCTACGTCGCCCTCGCCGAGGGCCTCGGCGTACC
GCTTATCACTTGCGACGGGCGACTTGCCCAATCCCATGGCCATAATGCGGAGATCGAGCTTGTCGCCTGA
GTGATCGTGTTGGACGCCTCGGCGGCCGTCGAGCTCATGCTCACGACGCCGGCGGGTGCGGCGGTCGCCCGGCGCTTGCG
GGGCGAAACCGTGCACGCCCCTGCACATTTCGATGTCGAGGTGATCGGGGCGATACGTCAAGCGGTCGTGCGTCAGCTGA
TCAGCGATCATGAAGGACTCGTCGTGGTTGTCAACTTCCTTAGCCTGCCCGTTCGGCGTTGGCCGTTAAAGCCATTCACC
CAGCGTGCCTATCAACTTCGGTCCACTCATACCGTGGCCGATGGAGCCTACGTCGCCCTCGCCGAGGGCCTCGGCGTACC
GCTTATCACTTGCGACGGGCGACTTGCCCAATCCCATGGCCATAATGCGGAGATCGAGCTTGTCGCCTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10191.69 Da Isoelectric Point: 9.6249
>AT237622 WP_120122374.1 NZ_CP093037:c916383-916099 [Bartonella krasnovii]
MKITPFKPEEYLKDIESQKIFLNEALKTGDAAHIADALGIVARAQNMSALAKETNRERSGLYRSLSKTGDPKLSTLVAVL
SALNLQLSVQSSTS
MKITPFKPEEYLKDIESQKIFLNEALKTGDAAHIADALGIVARAQNMSALAKETNRERSGLYRSLSKTGDPKLSTLVAVL
SALNLQLSVQSSTS
Download Length: 285 bp
>AT237622 NZ_LR882498:c1949690-1949463 [Mycobacterium tuberculosis variant microti]
ATGTCCGCCATGGTTCAGATCCGCAACGTTCCCGACGAGCTTCTCCACGAGCTGAAGGCCCGCGCAGCGGCGCAACGGAT
GAGCCTGAGCGATTTCCTCCTAGCACGGCTTGCCGAGATCGCGGAAGAACCGGCCCTCGACGACGTTCTCGACCGTCTAG
CGGCACTGCCGCGCCGGGATCTCGGCGCGAGCGCAGCCGAGCTTGTTGACGAGGCTCGATCTGAGTGA
ATGTCCGCCATGGTTCAGATCCGCAACGTTCCCGACGAGCTTCTCCACGAGCTGAAGGCCCGCGCAGCGGCGCAACGGAT
GAGCCTGAGCGATTTCCTCCTAGCACGGCTTGCCGAGATCGCGGAAGAACCGGCCCTCGACGACGTTCTCGACCGTCTAG
CGGCACTGCCGCGCCGGGATCTCGGCGCGAGCGCAGCCGAGCTTGTTGACGAGGCTCGATCTGAGTGA