Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) paaR-paaA-parE/ParE(toxin)
Location 1802238..1802713 Replicon chromosome
Accession NZ_CP093036
Organism Bartonella krasnovii strain B51_4

Toxin (Protein)


Gene name parE_1 Uniprot ID -
Locus tag MNL10_RS07750 Protein ID WP_120121236.1
Coordinates 1802238..1802525 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag MNL10_RS07755 Protein ID WP_120121238.1
Coordinates 1802525..1802713 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNL10_RS07725 (MNL10_07725) 1797847..1798365 - 519 WP_120121229.1 DUF1465 family protein -
MNL10_RS07730 (MNL10_07730) 1798566..1799708 - 1143 WP_120121231.1 OpgC domain-containing protein -
MNL10_RS07735 (MNL10_07735) 1799984..1800646 + 663 WP_120121233.1 thiamine phosphate synthase -
MNL10_RS07740 (MNL10_07740) 1801249..1801650 + 402 WP_120122708.1 helix-turn-helix transcriptional regulator -
MNL10_RS07745 (MNL10_07745) 1801657..1801878 + 222 WP_148255698.1 hypothetical protein -
MNL10_RS07750 (MNL10_07750) 1802238..1802525 - 288 WP_120121236.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MNL10_RS07755 (MNL10_07755) 1802525..1802713 - 189 WP_120121238.1 antitoxin Antitoxin
MNL10_RS07760 (MNL10_07760) 1803215..1803583 + 369 WP_241439948.1 helix-turn-helix transcriptional regulator -
MNL10_RS07765 (MNL10_07765) 1803964..1804333 + 370 Protein_1505 helix-turn-helix transcriptional regulator -
MNL10_RS07770 (MNL10_07770) 1804656..1805068 + 413 Protein_1506 hypothetical protein -
MNL10_RS07775 (MNL10_07775) 1806272..1807315 + 1044 WP_120121242.1 tetratricopeptide repeat protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11097.98 Da        Isoelectric Point: 10.1866

>T237621 WP_120121236.1 NZ_CP093036:c1802525-1802238 [Bartonella krasnovii]
MLPVVWLSSARDDLRQILTYIARENPSAARRMKRFLETSVLPLAEHPYLYRQSERILGLREIIAHPNYLILYRVAANQIE
IVAVVHARREFPTSL

Download         Length: 288 bp

>T237621 NZ_LR882498:1776131-1776535 [Mycobacterium tuberculosis variant microti]
ATGATCCTCATCGACACATCGGCCTGGGTGGAGTACTTCCGTGCCACCGGATCAATCGCCGCTGTCGAAGTACGCCGGCT
GCTGTCCGAAGAAGCAGCGCGAATCGCTATGTGTGAGCCCATTGCGATGGAAATCTTGAGTGGCGCGCTCGACGACAACA
CCCACACGACGCTAGAGCGGCTCGTGAATGGCTTGCCGTCGTTGAACGTTGATGACGCGATTGACTTTCGTGCTGCCGCG
GGTATCTATCGCGCCGCCCGGCGCGCCGGCGAAACGGTTCGAAGCATCAACGACTGCCTCATAGCGGCGCTCGCGATCCG
CCACGGTGCGCGTATCGTCCACCGTGACGCCGACTTTGATGTGATTGCCCGGATTACCAACCTGCAGGCCGCATCGTTTC
GGTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7068.01 Da        Isoelectric Point: 4.3167

>AT237621 WP_120121238.1 NZ_CP093036:c1802713-1802525 [Bartonella krasnovii]
MKNTLSPFISEFETIEQESSHTAWLRDKVAISLANLSPPIPHDEVMAEMDVIISQLENEQKK

Download         Length: 189 bp

>AT237621 NZ_LR882498:1775922-1776125 [Mycobacterium tuberculosis variant microti]
ATGTCGCGCACCAACATCGACATCGATGACGAACTTGCCGCCGAGGTCATGCGCAGGTTCGGTCTGACCACCAAGAGGGC
GGCGGTCGACCTTGCCCTACGACGGTTGGTCGGGTCGCCGTTGAGCCGTGAGTTTCTGCTCGGGCTGGAAGGCGTCGGCT
GGGAAGGCGACCTGGATGACTTGCGAAGCGATCGCCCAGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References